TRPM2 antibody (AA 60-119)
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- Target See all TRPM2 Antibodies
- TRPM2 (Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))
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Binding Specificity
- AA 60-119
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TRPM2 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Transient receptor potential cation channel subfamily M member 2 protein (60-119AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- TRPM2 (Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))
- Alternative Name
- TRPM2 (TRPM2 Products)
- Synonyms
- EREG1 antibody, KNP3 antibody, LTRPC2 antibody, NUDT9H antibody, NUDT9L1 antibody, TRPC7 antibody, Trpm2-predicted antibody, TRPM2 antibody, si:ch73-263b18.1 antibody, 9830168K16Rik antibody, C79133 antibody, Trp7 antibody, Trrp7 antibody, transient receptor potential cation channel subfamily M member 2 antibody, transient receptor potential cation channel, subfamily M, member 2 antibody, transient receptor potential cation channel subfamily C member 7 antibody, TRPM2 antibody, Trpm2 antibody, trpm2 antibody, TRPC7 antibody
- Background
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Background: Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.
Aliases: EREG 1 antibody, EREG1 antibody, Estrogen responsive element associated gene 1 antibody, Estrogen responsive element associated gene 1 protein antibody, Estrogen-responsive element-associated gene 1 protein antibody, KNP 3 antibody, KNP3 antibody, Long transient receptor potential channel 2 antibody, LTRPC 2 antibody, LTrpC-2 antibody, LTrpC2 antibody, MGC133383 antibody, NUDT9H antibody, NUDT9L1 antibody, putative Ca2+ channel protein antibody, putative Ca2+ channel protein antibody, Transient receptor potential cation channel subfamily M member 2 antibody, Transient receptor potential channel 7 antibody, TRPC 7 antibody, TrpC7 antibody, TRPM 2 antibody, Trpm2 antibody, TRPM2_HUMAN antibody
- UniProt
- O94759
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