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anti-phosphofructokinase, Muscle (PFKM) Antibodies

Three phosphofructokinase isozymes exist in humans muscle, liver and platelet. Additionally we are shipping phosphofructokinase, Muscle Kits (21) and phosphofructokinase, Muscle Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PFKM 5213 P08237
PFKM 18642 P47857
PFKM 65152 P47858
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Top anti-phosphofructokinase, Muscle Antibodies at antibodies-online.com

Showing 10 out of 86 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PFKM AntibodyTitration: 1.0 µg/mL  Positive Control: Fetal Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Rabbit Un-conjugated IHC (p), WB   50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details

PFKM Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-phosphofructokinase, Muscle Antibodies

  1. Human Polyclonal PFKM Primary Antibody for EIA, IHC (p) - ABIN360633 : Howard, Akots, Bowden: Physical and genetic mapping of the muscle phosphofructokinase gene (PFKM): reassignment to human chromosome 12q. in Genomics 1996 (PubMed)
    Show all 2 references for ABIN360633

  2. Human Monoclonal PFKM Primary Antibody for EIA, WB - ABIN1449415 : Martínez-Costa, Sánchez-Martínez, Sánchez, Aragón: Chimeric phosphofructokinases involving exchange of the N- and C-terminal halves of mammalian isozymes: implications for ligand binding sites. in FEBS letters 2007 (PubMed)
    Show all 2 references for ABIN1449415

  3. Human Polyclonal PFKM Primary Antibody for EIA, IHC (p) - ABIN360632 : Vasconcelos, Sivakumar, Dalakas, Quezado, Nagle, Leon-Monzon, Dubnick, Gajdusek, Goldfarb: Nonsense mutation in the phosphofructokinase muscle subunit gene associated with retention of intron 10 in one of the isolated transcripts in Ashkenazi Jewish patients with Tarui disease. in Proceedings of the National Academy of Sciences of the United States of America 1995 (PubMed)
    Show all 2 references for ABIN360632

More Antibodies against phosphofructokinase, Muscle Interaction Partners

Human phosphofructokinase, Muscle (PFKM) interaction partners

  1. Data indicate that 6-phosphofructo-2-kinase (show PFKFB3 Antibodies)/fructose-2,6-biphosphatase3 (PFKFB3 (show PFKFB3 Antibodies)) and phosphofructokinase (PFK1) expression allows discrimination between induced pluripotent stem cells (iPS (show SLC27A4 Antibodies)) and cancer stem cells (CSCs).

  2. characterize three PFK1 mutations and show they have distinct effects on allosteric regulation of PFKP (show PFKP Antibodies) activity and lactate production.

  3. Gene-based analysis identified an association between breast cancer and the phosphofructokinase-muscle (PFKM) gene on chromosome 12q13.11 that met the genome-wide gene-based threshold of 2.5 x 10(-6).

  4. insulin (show INS Antibodies)/phosphofructokinase (PFKM), overlaps with an expression quantitative trait loci

  5. Asp (show ASIP Antibodies)(543)Ala, a naturally occurring Tarui disease-causing mutation in the activating binding site, causes an increased efficacy of ATP at the inhibitory allosteric binding site.

  6. Molecular genetic findings demonstrated the absence of specific genotype-phenotype correlations in PFKM gene mutations.

  7. eukaryotic Pfk did not evolve from prokaryotic ancestors, reciprocal linkage of functionally opposed allosteric binding sites must have developed independently in prokaryotic and eukaryotic Pfk (convergent evolution).

  8. Posttranslational modification of PFK1 enzyme might be the pivotal factor of deregulated glycolytic flux in tumors

  9. Data indicate that substitution of residue at the citrate-binding site (D591V) of PFK-M resulted in the complete loss of activity.

  10. Glycolytic efficiency, which is important for the survival of cancer cells, depends primarily on the preferential expression of PFK-L over the M and P isoforms.

Mouse (Murine) phosphofructokinase, Muscle (PFKM) interaction partners

  1. These results reveal a novel role of NRX in the regulation of PFK1 activity and in the balance between glycolysis and the pentose phosphate pathway.

  2. Posttranslational modification of PFK1 enzyme might be the pivotal factor of deregulated glycolytic flux in tumors.

  3. HK1S is tethered in the principal piece region by PFKMS, which in turn is bound tightly to GSTM5 (show GSTM5 Antibodies) in the fibrous sheath of sperm.

  4. Recombinant expression of caveolin-3 (show CAV3 Antibodies) affects subcellular localization of PFK-M, by targeting PFK-M to plasma membrane and by trans-locating PFK-M to caveolae-enriched membrane domains. Strictly dependent on the concentration of extracellular glucose.

  5. Identification of novel PFK-M transcripts in the testis and embryo.

  6. Sequence analysis of Pfkm gene introns and exons was performed.

  7. The results suggest the importance of phosphofructokinase-M for insulin (show INS Antibodies) secretion, although glucokinase (show GCK Antibodies) is the overall rate-limiting glucose sensor.

  8. Thr-201 phosphorylation of Bad by JNK1 is required for PFK-1 activation

  9. In skeletal muscle, the lack of PFK activity blocked glycolysis and resulted in considerable glycogen (show GYS1 Antibodies) storage and low ATP content.

Horse (Equine) phosphofructokinase, Muscle (PFKM) interaction partners

  1. The tissue expression profiles of eGYS1, equine type II hexokinase (eHKII) and muscle-type phosphofructokinase (ePFKM) were determined by real-time PCR and western blot analysis.

Rabbit phosphofructokinase, Muscle (PFKM) interaction partners

  1. Posttranslational modification of PFK1 enzyme might be the pivotal factor of deregulated glycolytic flux in tumors.

phosphofructokinase, Muscle (PFKM) Antigen Profile

Protein Summary

Three phosphofructokinase isozymes exist in humans muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with PFKM

  • phosphofructokinase, muscle (PFKM) antibody
  • phosphofructokinase, liver (PFKL) antibody
  • phosphofructokinase, muscle (Pfkm) antibody
  • phosphofructokinase, platelet (PFKP) antibody
  • AI131669 antibody
  • GSD7 antibody
  • M-PFK antibody
  • PFK-1 antibody
  • Pfk-4 antibody
  • PFK-A antibody
  • Pfk-M antibody
  • PFK1 antibody
  • Pfk4 antibody
  • Pfka antibody
  • PFKM antibody
  • Pfkx antibody

Protein level used designations for PFKM

6-phosphofructokinase, muscle type , PFK-A , phosphofructo-1-kinase isozyme A , phosphofructokinase 1 , phosphofructokinase-M , phosphohexokinase , 6-phosphofructokinase, liver type , PFK-B , liver-type 1-phosphofructokinase , phosphofructo-1-kinase isozyme B , phosphofructokinase, liver type , 6-phosphofructo-1-kinase , phosphofructokinase, polypeptide X , phosphofructokinase 4 , phosphofructokinase-1 A isozyme , phosphofructokinase-M (connecting peptide) , phosphofructokinase-A , 6-phosphofructokinase muscle type , muscle type phosphofructokinase , muscle-type phosphofructokinase , muscle phosphofructokinase , 6-phosphofructokinase type C , PFK-C , phosphofructo-1-kinase isozyme C , phosphofructokinase C isozyme , phosphofructokinase, muscle

GENE ID SPECIES
451863 Pan troglodytes
100172585 Pongo abelii
508683 Bos taurus
5213 Homo sapiens
18642 Mus musculus
65152 Rattus norvegicus
506544 Bos taurus
403849 Canis lupus familiaris
100034116 Equus caballus
733601 Sus scrofa
100345647 Oryctolagus cuniculus
374064 Gallus gallus
100733625 Cavia porcellus
100009526 Oryctolagus cuniculus
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