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Browse our anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) Antibodies

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anti-Heat Shock 60kDa Protein 1 (Chaperonin) Antibodies (HSPD1)
On are 666 Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) Antibodies from 33 different suppliers available. Additionally we are shipping Heat Shock 60kDa Protein 1 (Chaperonin) Kits (67) and Heat Shock 60kDa Protein 1 (Chaperonin) Proteins (32) and many more products for this protein. A total of 777 Heat Shock 60kDa Protein 1 (Chaperonin) products are currently listed.
12, 60kDa, BP5, cb863, CG12101, chaperonin, CPN60, crpA, d-hsp60, Dmel\\CG12101, Dmhsp60, fa04a05, fb22d10, fi27b05, G62, GROEL, groL, HLD4, HSP-60, Hsp60, hsp60A, HSP65, HSPD1, Hspd1-30p, HuCHA60, id:ibd2197, IEF16, l(1)10Ac, l(1)BP5, l(1)dp025, l(1)G8, l(1)HM21, l(1)L12, MIF4, Mmp-P1, MNA2, mopA, sb:cb144, SPG13, SSP 7506, wu:fa04a05, wu:fb22d10, wu:fi04a12, wu:fi27b05
list all antibodies Gene Name GeneID UniProt
Anti-Human HSPD1 HSPD1 3329 P10809
Anti-Mouse HSPD1 HSPD1 15510 P63038
Anti-Rat HSPD1 HSPD1 63868 P63039

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All available anti-Heat Shock 60kDa Protein 1 (Chaperonin) Antibodies

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Top referenced anti-Heat Shock 60kDa Protein 1 (Chaperonin) Antibodies

  1. Chicken Monoclonal HSPD1 Primary Antibody for FACS, IP - ABIN361784 : Verda, Kim, Ikehara, Statkute, Bronesky, Petrenko, Oyama, He, Link, Vahanian, Burt: Hematopoietic mixed chimerism derived from allogeneic embryonic stem cells prevents autoimmune diabetes mellitus in NOD mice. in Stem cells (Dayton, Ohio) 2008 (PubMed)
    Show all 17 references for ABIN361784

  2. Bacteria Monoclonal HSPD1 Primary Antibody for FACS, IHC - ABIN361786 : Bason, Corrocher, Lunardi, Puccetti, Olivieri, Girelli, Navone, Beri, Millo, Margonato, Martinelli, Puccetti: Interaction of antibodies against cytomegalovirus with heat-shock protein 60 in pathogenesis of atherosclerosis. in Lancet (London, England) 2003 (PubMed)
    Show all 16 references for ABIN361786

  3. Bacteria Monoclonal HSPD1 Primary Antibody for FACS, IHC (fro) - ABIN263948 : Hartl: Molecular chaperones in cellular protein folding. in Nature 1996 (PubMed)
    Show all 11 references for ABIN263948

  4. Human Monoclonal HSPD1 Primary Antibody for BI, WB - ABIN968590 : Ohashi, Burkart, Flohé, Kolb: Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 5 references for ABIN968590

  5. Chicken Monoclonal HSPD1 Primary Antibody for IHC (p), IP - ABIN1107605 : Hansen, Bross, Westergaard, Nielsen, Eiberg, Børglum, Mogensen, Kristiansen, Bolund, Gregersen: Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter. in Human genetics 2002 (PubMed)
    Show all 3 references for ABIN1107605

  6. Human Monoclonal HSPD1 Primary Antibody for ICC, FACS - ABIN969200 : López-Hoyos, Alvarez, Ruiz Soto, Blanco, José Bartolomé, Martínez-Taboada: Serum levels of antibodies to Chlamydia pneumoniae and human HSP60 in giant cell arteritis patients. in Clinical and experimental rheumatology 2009 (PubMed)
    Show all 2 references for ABIN969200

  7. Human Monoclonal HSPD1 Primary Antibody for EIA, IHC (p) - ABIN263916 : Cheng, Hartl, Horwich: The mitochondrial chaperonin hsp60 is required for its own assembly. in Nature 1991 (PubMed)
    Show all 2 references for ABIN263916

  8. Human Polyclonal HSPD1 Primary Antibody for IF, WB - ABIN389380 : Venner, Singh, Gupta: Nucleotide sequences and novel structural features of human and Chinese hamster hsp60 (chaperonin) gene families. in DNA and cell biology 1991 (PubMed)
    Show all 2 references for ABIN389380

  9. Guinea Pig Polyclonal HSPD1 Primary Antibody for WB - ABIN2792215 : Hewamadduma, Kirby, Kershaw, Martindale, Dalton, McDermott, Shaw: HSP60 is a rare cause of hereditary spastic paraparesis, but may act as a genetic modifier. in Neurology 2008 (PubMed)

More Antibodies against Heat Shock 60kDa Protein 1 (Chaperonin) Interaction Partners

Fruit Fly (Drosophila melanogaster) Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) interaction partners

  1. Expression of HSP60A is post-transcriptionally regulated in a highly dynamic pattern during embryogenesis, even under heat-shock conditions. In contrast, in very stressful situations, its expression is upregulated transcriptionally over the entire embryo.

Zebrafish Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) interaction partners

  1. Heat-shock protein 60 (show HSP60 Antibodies) is required for blastema formation and maintenance during regeneration.

Human Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) interaction partners

  1. Data show that the interaction between cell cycle and apoptosis regulator 2 (CCAR2) and heat shock protein 60 (Hsp60) increases in the presence of rotenone.

  2. NIP (show GIPC1 Antibodies)-SNAP-1 (show NIPSNAP3B Antibodies) and -2 localized in the mitochondrial inner membrane space, whereas HSP60 localized in the matrix. Expression levels of NIP (show GIPC1 Antibodies)-SNAP-1 (show NIPSNAP3B Antibodies) and -2 in cells were decreased by knockdown of HSP60, but not HSP10 (show HSPE1 Antibodies). The findings indicate that HSP60 promotes folding and maintains the stability of NIP (show GIPC1 Antibodies)-SNAP-1 (show NIPSNAP3B Antibodies) and -2.

  3. In this instance, the ATP5B (show ATP5B Antibodies)/CALR (show CALR Antibodies)/HSP90B1 (show HSP90B1 Antibodies)/HSPB1 (show HSPB1 Antibodies)/HSPD1-signaling network was revealed as the predominant target which was associated with the majority of the observed protein-protein interactions. As a result, the identified targets may be useful in explaining the anticancer mechanisms of ursolic acid and as potential targets for colorectal cancer therapy.

  4. Hsp10 (show HSPE1 Antibodies) and Hsp60 may be implicated in carcinogenesis from its very early steps in colorectal cancer.

  5. High HSP60 expression is associated with gastric cancer.

  6. Elevated expression of HSPD1 in osteosarcoma tissues correlated with poor prognosis of the osteosarcoma patients.

  7. The cardioprotective effect of 40-60 g/d of alcohol consumption could be due in part, to increased intracellular HSPA1A (show HSPA1A Antibodies), a potent anti-inflammatory protein. Excessive intake of alcohol increases antibodies anti-Hsp60, stimulating proinflammatory cytokines. This fact may explain the mortality from cardiovascular disease in heavy drinkers.

  8. This review article presents accumulating proof that supports the idea that tolerization with antigenic HSP60 protein or its peptides may arrest or even prevent atherosclerosis by increased production of regulatory T cells and/or anti-inflammatory cytokines. [review]

  9. Data show that Eclipta extract upregulates heat shock protein 60 (Hsp60) which is localized in the endoplasmic reticulum (ER).

  10. Data indicate that on addition of the heat-shock proteins GroEL (show GroEL Antibodies)-GroES (show HSPE1 Antibodies) molecular chaperone (show HSP90AA1 Antibodies) system, the folding of the nascent chemokine receptor (show CCR1 Antibodies) type 5 (CCR5 (show CCR5 Antibodies)) was significantly enhanced.

Pig (Porcine) Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) interaction partners

  1. Wild type HSP60 displayed a heptameric single-ring structure in the absence of ATP. In contrast, HSP60 formed mainly a "football-type" complex with HSP10 (show HSPE1 Antibodies) in the presence of ATP and mediated the refolding of denatured substrate protein.

  2. These results indicate that different tissues had different sensitivities to transport stress, possibly resulting in varying levels of cytoprotection by Hsp60 in the different tissues.

Cow (Bovine) Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) interaction partners

  1. This paper reports the localization of both GRP78 (show HSPA5 Antibodies) and HSP60 on the luminal/apical surface of oviduct epithelial cells, their binding to spermatozoa, and the presence of endogenous HSP60 in the sperm midpiece.

Mouse (Murine) Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) interaction partners

  1. Overexpressing hsp60 in cultured myoblasts induced only the expression of PGC1 (show PPARGC1A Antibodies) 1alpha, suggesting a correlation between Hsp60 overexpression and PGC1 (show PPARGC1A Antibodies) 1 alpha activation.

  2. neonatal heart failure through HSP60 induction likely involves developmental defects and excessive apoptosis

  3. Heat shock protein 60 stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 (show TLR4 Antibodies) and ERK MAPK (show MAPK1 Antibodies) activation

  4. TLR4 (show TLR4 Antibodies) mediates HSP60-associated apoptosis and that HSP60 has an important role in cardiac myocyte injury, both apoptotic and necrotic.

  5. a direct toxic effect of heat shock protein 60 towards neurons and oligodendrocytes in the CNS involving Toll (show TLR4 Antibodies)-like receptor4 and MyD88 (show MYD88 Antibodies) pathways

  6. Dietary wolfberry elevated the xanthophyll concentrations and enhanced expression of BCO2 (show BCO2 Antibodies) and heat shock protein 60, activated AMPKalpha2 (show PRKAA2 Antibodies), potentiated mitophagy and mitochondrial biogenesis and enhanced lipid oxidation and secretion in the liver of mice.

  7. It is concluded that nasal administration of HSP60 can inhibit atherosclerotic formation through immune tolerance which is established by Tregs depending on the induction of anti-inflammatory cytokine TGF-beta (show TGFB1 Antibodies).

  8. MnSOD (show SOD2 Antibodies) is a substrate of the Hsp60 folding machinery.

  9. In type 2 diabetes, there is hypothalamic insulin (show INS Antibodies) resistance and mitochondrial dysfunction due to downregulation of the mitochondrial chaperone HSP60. HSP60 reduction was due to a lack of proper leptin (show LEP Antibodies) signaling and was restored by leptin (show LEP Antibodies) treatment.

  10. Data indicate that HMGB1 (show HMGB1 Antibodies) and HSP60 are expressed in a Myd88 (show MYD88 Antibodies) dependent manner.

Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) Antigen Profile

Antigen Summary

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.

Alternative names and synonyms associated with Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1)

  • Heat shock protein 60 (Hsp60) antibody
  • heat shock 60kDa protein 1 (chaperonin) (HSPD1) antibody
  • heat shock 60kDa protein 1 (chaperonin) (hspd1) antibody
  • chaperone ATPase HSP60 (HSP60) antibody
  • molecular chaperone GroEL (groEL) antibody
  • chaperonin GroEL (hsp60) antibody
  • molecular chaperone GroEL (groEl) antibody
  • chaperonin GroEL (groEL) antibody
  • mitochondrial chaperonin (HSP60) antibody
  • heat shock protein 60 (hsp60) antibody
  • heat shock 60kD protein 1 (chaperonin) (hspd1) antibody
  • heat shock protein 1 (chaperonin) (Hspd1) antibody
  • 12 antibody
  • 60kDa antibody
  • BP5 antibody
  • cb863 antibody
  • CG12101 antibody
  • chaperonin antibody
  • CPN60 antibody
  • crpA antibody
  • d-hsp60 antibody
  • Dmel\\CG12101 antibody
  • Dmhsp60 antibody
  • fa04a05 antibody
  • fb22d10 antibody
  • fi27b05 antibody
  • G62 antibody
  • GROEL antibody
  • groL antibody
  • HLD4 antibody
  • HSP-60 antibody
  • Hsp60 antibody
  • hsp60A antibody
  • HSP65 antibody
  • HSPD1 antibody
  • Hspd1-30p antibody
  • HuCHA60 antibody
  • id:ibd2197 antibody
  • IEF16 antibody
  • l(1)10Ac antibody
  • l(1)BP5 antibody
  • l(1)dp025 antibody
  • l(1)G8 antibody
  • l(1)HM21 antibody
  • l(1)L12 antibody
  • MIF4 antibody
  • Mmp-P1 antibody
  • MNA2 antibody
  • mopA antibody
  • sb:cb144 antibody
  • SPG13 antibody
  • SSP 7506 antibody
  • wu:fa04a05 antibody
  • wu:fb22d10 antibody
  • wu:fi04a12 antibody
  • wu:fi27b05 antibody

Protein level used designations for HSPD1

60-kDa heat shock protein, mitochondrial , CG12101-PA , CG12101-PB , Hsp 60 , Hsp60-PA , Hsp60-PB , heat shock protein 60 , heat shock protein 60 kDa , lethal(1)10Ac , mitochondrial matrix protein P1 , 60 kDa heat shock protein, mitochondrial , chaperonin , heat shock 60kDa protein 1 (chaperonin) , 60 kDa heat shock protein, mitochondrial-like , chaperonin GroEL , mitochondrial chaperonin , hsp60 , nbl , no blastema , 60 kDa chaperonin , P60 lymphocyte protein , chaperonin 60 , heat shock protein 65 , short heat shock protein 60 Hsp60s1 , CPN60 , HSP-60 , heat shock 60 kDa protein 1 , mitochondrial heat shock 60 kDa protein 1 , HSP-65 , heat shock protein, 60 kDa , heat shock 60kD protein 1 (chaperonin) , heat shock 60kDa protein 1 , heat shock protein 60 (liver)

32045 Drosophila melanogaster
459852 Pan troglodytes
693438 Macaca mulatta
100124945 Xenopus (Silurana) tropicalis
100349912 Oryctolagus cuniculus
100414401 Callithrix jacchus
100604694 Nomascus leucogenys
850963 Saccharomyces cerevisiae S288c
1173196 Yersinia pestis CO92
2761905 Methanococcus maripaludis S2
2780418 Candidatus Protochlamydia amoebophila UWE25
2859943 Staphylococcus aureus subsp. aureus MRSA252
2955745 Yersinia pseudotuberculosis IP 32953
4714365 Yersinia enterocolitica subsp. enterocolitica 8081
7442965 Thalassiosira pseudonana CCMP1335
100136430 Salmo salar
698024 Macaca mulatta
100477321 Ailuropoda melanoleuca
282676 Danio rerio
3329 Homo sapiens
424059 Gallus gallus
492279 Sus scrofa
511913 Bos taurus
478854 Canis lupus familiaris
399217 Xenopus laevis
100174117 Pongo abelii
15510 Mus musculus
63868 Rattus norvegicus
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