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BAD antibody (pSer155)

BAD Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1355821
  • Target See all BAD Antibodies
    BAD (BCL2-Associated Agonist of Cell Death (BAD))
    Binding Specificity
    • 34
    • 34
    • 27
    • 27
    • 26
    • 24
    • 24
    • 23
    • 15
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    pSer155
    Reactivity
    • 375
    • 219
    • 141
    • 17
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 446
    • 15
    • 1
    Rabbit
    Clonality
    • 428
    • 34
    Polyclonal
    Conjugate
    • 179
    • 41
    • 37
    • 35
    • 34
    • 31
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This BAD antibody is un-conjugated
    Application
    • 253
    • 243
    • 163
    • 95
    • 81
    • 80
    • 57
    • 55
    • 22
    • 19
    • 13
    • 10
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    The antibody detects endogenous level of BAD only when phosphorylated at serine 155.
    Immunogen
    Peptide sequence around phosphorylation site of pSer155 (R-M-S (p) -D-E) derived from Human BAD. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
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  • Application Notes
    Western blotting: 1:500
    Immunohistochemistry: 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at -20 °C
  • Target
    BAD (BCL2-Associated Agonist of Cell Death (BAD))
    Alternative Name
    BAD (BAD Products)
    Synonyms
    bad antibody, fa01b12 antibody, wu:fa01b12 antibody, wu:fa96d04 antibody, BAD antibody, BBC2 antibody, BCL2L8 antibody, AI325008 antibody, Bbc2 antibody, BCL2-associated agonist of cell death b antibody, BCL2 associated agonist of cell death antibody, BCL2-associated agonist of cell death antibody, badb antibody, BAD antibody, Bad antibody
    Background
     Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
    Molecular Weight
    23 kDa
    NCBI Accession
    NM_007522, NP_031548
    UniProt
    Q61337
    Pathways
    MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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