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MDM2 antibody (pSer186, pSer188)
MDM2
Reactivity: Human
ELISA, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MDM2 Antibody
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Target
See all MDM2 Antibodies
MDM2
(Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
Binding Specificity
All epitopes for MDM2 antibodies
pSer186, pSer188
Reactivity
All reactivities for MDM2 antibodies
Human
Host
All hosts for MDM2 antibodies
Rabbit
Clonality
All clonalities for MDM2 antibodies
Polyclonal
Conjugate
All conjugates for MDM2 antibodies
This MDM2 antibody is un-conjugated
Application
All applications for MDM2 antibodies
ELISA, Immunofluorescence (IF)
Specificity
Epitopes for Species: H:S186+S188
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human MDM2 around the phosphorylation site of serine 186 and serine 188 (H-K-SP-D-SP-I-S).
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1 mg/mL
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Storage
-20 °C
Storage Comment
Store at -20°C / 1 year
Expiry Date
12 months
Target Details for MDM2
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Target
MDM2
(Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
Alternative Name
MDM2 (MDM2 Products )
Synonyms
ACTFS antibody, HDMX antibody, hdm2 antibody, zgc:109834 antibody, 1700007J15Rik antibody, AA415488 antibody, Mdm-2 antibody, MDM2 proto-oncogene antibody, MDM2 proto-oncogene S homeolog antibody, Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) antibody, MDM2 oncogene, E3 ubiquitin protein ligase antibody, transformed mouse 3T3 cell double minute 2 antibody, MDM2 antibody, mdm2.S antibody, Mdm2 antibody, mdm2 antibody
Background
Double minute 2 protein, EC 6.3.2.-, Oncoprotein Mdm2, Ubiquitin-protein ligase E3 Mdm2, p53-binding protein Mdm2
UniProt
Q00987
Pathways
p53 Signaling , PI3K-Akt Signaling , Cell Division Cycle , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Autophagy , Ubiquitin Proteasome Pathway
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