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Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (Tyr701) antibody

Details for Product No. ABIN197172
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Antigen
Synonyms IMUP, H2RSP, IMUP-1, IMUP-2, 2010005J02Rik, AA408197, DD6G4-4, CANDF7, ISGF-3, STAT91, STAT4, XStat1, STAT, STAT1, dZ182H3.3, si:by134g18.2, si:by51f19.1, si:dz182h3.3, si:dz199m19.1, si:dz73o4.2
Epitope
Tyr701
(54), (51), (48), (14), (9), (9), (9), (5), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(311), (163), (149), (43), (41), (29), (27), (4), (2), (1), (1)
Host
Rabbit
(260), (62), (4), (4), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(7), (6), (6), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(291), (114), (97), (78), (65), (30), (28), (26), (7), (4), (4), (2), (1), (1)
Pubmed 6 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

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Catalog No. ABIN197172
308.00 $
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human STAT1 around the phosphorylation site of tyrosine 701(T-G-YP-I-K).
Specificity STAT1 antibody detects endogenous levels of total STAT1 protein.
Purification Affinity-chromatography using epitope-specific immunogen
Alternative Name STAT1
Background Alternate names: Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84
NCBI Accession 9606
UniProt P42224
Research Area Cancer, Transcription Factors, Signaling, Receptors, Inflammation
Application Notes Western Blot: 1: 500~1: 1000. Immunohistochemistry: 1: 50~1: 100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS(without Mg2+ and Ca2+), pH 7.4 containing 150mM NaCl, 0.02% sodium azide and 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Expiry Date 12 months
Supplier Images
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (Tyr701) antibody anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (Tyr701) antibody
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (Tyr701) antibody (2) anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (Tyr701) antibody (Image 2)
Background publications Wakao, Gouilleux, Groner: "Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response." in: The EMBO journal, Vol. 13, Issue 9, pp. 2182-91, 1994 (PubMed).

Ihle, Witthuhn, Quelle et al.: "Signaling by the cytokine receptor superfamily: JAKs and STATs." in: Trends in biochemical sciences, Vol. 19, Issue 5, pp. 222-7, 1994 (PubMed).

Meraz, White, Sheehan et al.: "Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway." in: Cell, Vol. 84, Issue 3, pp. 431-42, 1996 (PubMed).

Durbin, Hackenmiller, Simon et al.: "Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease." in: Cell, Vol. 84, Issue 3, pp. 443-50, 1996 (PubMed).

Heim: "The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus." in: Journal of receptor and signal transduction research, Vol. 19, Issue 1-4, pp. 75-120, 1999 (PubMed).

Demoulin, Van Roost, Stevens et al.: "Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9." in: The Journal of biological chemistry, Vol. 274, Issue 36, pp. 25855-61, 1999 (PubMed).

Validation Images
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