GCKR antibody (C-Term)
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- Target See all GCKR Antibodies
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GCKR antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PIALLSLLFR CSITEAQAHL AAAPSVCEAV RSALAGPGQK RTADPLEILE
- Predicted Reactivity
- Human: 100%, Rat: 79%
- Characteristics
- This is a rabbit polyclonal antibody against GCKR. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product GCKR Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 625 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
- Alternative Name
- GCKR (GCKR Products)
- Synonyms
- FGQTL5 antibody, GKRP antibody, GLRE antibody, gckr antibody, glucokinase regulator antibody, glucokinase regulatory protein antibody, glucokinase regulator L homeolog antibody, GCKR antibody, Gckr antibody, gckr.L antibody
- Background
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This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Alias Symbols: GKRP, FGQTL5
Protein Interaction Partner: CDKN1A, UBC, TRAF2, GCK,
Protein Size: 625 - Molecular Weight
- 68 kDa
- Gene ID
- 2646
- NCBI Accession
- NM_001486, NP_001477
- UniProt
- Q14397
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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