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c-MYC antibody

MYC Reactivity: Human, Mouse, Zebrafish (Danio rerio) WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN357365
  • Target See all c-MYC (MYC) Antibodies
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Reactivity
    • 373
    • 169
    • 123
    • 15
    • 14
    • 13
    • 13
    • 13
    • 9
    • 9
    • 8
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Zebrafish (Danio rerio)
    Host
    • 296
    • 97
    • 7
    • 3
    • 2
    • 1
    Rabbit
    Clonality
    • 287
    • 118
    Polyclonal
    Conjugate
    • 195
    • 32
    • 27
    • 26
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This c-MYC antibody is un-conjugated
    Application
    • 305
    • 142
    • 96
    • 83
    • 80
    • 63
    • 58
    • 28
    • 26
    • 17
    • 14
    • 13
    • 12
    • 11
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects MYC.
    Purification
    Protein A column, followed by peptide affinity purification
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding T58 of human MYC.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MYC Primary Antibody
  • Application Notes
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Alternative Name
    C-Myc (MYC Products)
    Synonyms
    MRTL antibody, MYCC antibody, bHLHe39 antibody, c-Myc antibody, CMYC antibody, c-myc antibody, C-MYC antibody, LOC100136746 antibody, ARC antibody, B430311C09Rik antibody, MYC antibody, NOP antibody, Nop30 antibody, RNCMYC antibody, mMyc antibody, AU016757 antibody, Myc2 antibody, Niard antibody, Nird antibody, cmyc antibody, zc-myc antibody, c-myc II antibody, myc-B antibody, myc2 antibody, myc1 antibody, CMyc antibody, zgc:55680 antibody, CG10798 antibody, D-Myc antibody, DM antibody, DMYc antibody, Dm antibody, Dmel\CG10798 antibody, Dmyc antibody, EG:BACN5I9.1 antibody, anon-WO03040301.171 antibody, bHLHe57 antibody, c-MYC antibody, d-myc antibody, dMYC antibody, dMyc antibody, dMyc1 antibody, da antibody, dm antibody, dm/dMyc antibody, dm/myc antibody, dmyc antibody, dmyc1 antibody, l(1)G0139 antibody, l(1)G0354 antibody, l(1)G0359 antibody, myc antibody, MYC proto-oncogene, bHLH transcription factor antibody, v-myc myelocytomatosis viral oncogene homolog antibody, nucleolar protein 3 (apoptosis repressor with CARD domain) antibody, myelocytomatosis oncogene antibody, MYC proto-oncogene, bHLH transcription factor a antibody, MYC proto-oncogene, bHLH transcription factor L homeolog antibody, MYC proto-oncogene, bHLH transcription factor S homeolog antibody, v-myc myelocytomatosis viral oncogene homolog (avian) antibody, MYC proto-oncogene, bHLH transcription factor b antibody, CG10798 gene product from transcript CG10798-RB antibody, MYC antibody, LOC100136746 antibody, Nol3 antibody, Myc antibody, myca antibody, myc.L antibody, myc.S antibody, mycb antibody
    Background
    MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of the gene encoding MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.Synonyms: BHLHE39, Class E basic helix-loop-helix protein 39, Myc proto-oncogene protein, Transcription factor p64
    Molecular Weight
    48804 Da
    Gene ID
    4609, 9606
    UniProt
    P01106
    Pathways
    p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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