GJB6 antibody (AA 221-234)

Catalog No. ABIN490596

Product Details anti-GJB6 Antibody

Target: GJB6 (Gap Junction Protein, beta 6, 30kDa (GJB6))

Binding Specificity: AA 221-234

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This GJB6 antibody is un-conjugated

Application: ELISA

Specificity: Human GJB6. Reported variants represent identical protein: NP_006774.2, NP_001103691.1, NP_001103689.1, NP_001103690.1

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla (100%) Gibbon, Monkey (93%) Marmoset, Panda, Bovine, Horse (86%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-RSKRAQTQKNHPNH from an internal region of human GJB6 (NP_006774.2). Percent identity by BLAST analysis: Human, Gorilla (100%), Gibbon, Monkey (93%), Marmoset, Panda, Bovine, Horse (86%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:16000)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Preliminary experiments gave an approx 14  kDa band in Human Brain (Cerebellum) and Rat Brain lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 30.4  kDa according to NP_006774.2. The 14  kDa band was successfully blocked by incubation with the immunizing peptide.

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for GJB6

Target: GJB6 (Gap Junction Protein, beta 6, 30kDa (GJB6))

Alternative Name: GJB6 / CX30 / Connexin 30 (GJB6 Products)

Synonyms: connexin-26 antibody, cx26 antibody, cx30 antibody, dfna3 antibody, dfna3a antibody, dfnb1 antibody, dfnb1a antibody, ed2 antibody, edh antibody, gjb6 antibody, hed antibody, nsrd1 antibody, ppk antibody, AA958971 antibody, Cx30 antibody, D14Bwg0506e antibody, CX30 antibody, DFNA3 antibody, DFNA3B antibody, DFNB1B antibody, ECTD2 antibody, ED2 antibody, EDH antibody, HED antibody, HED2 antibody, CX31 antibody, connexin 30 antibody, gap junction protein beta 2 antibody, gap junction protein beta 6 antibody, gap junction protein, beta 6 antibody, LOC387566 antibody, gjb2 antibody, GJB6 antibody, Gjb6 antibody

Background: Name/Gene ID: GJB6
Subfamily: Connexin
Family: Ion Channel

Synonyms: GJB6, DFNB1B, ECTD2, EDH, Connexin-30, DFNA3, Gap junction beta-6 protein, Gap Junction protein beta-6, Hed, HED2, Connexin 30, CX30, DFNA3B, ED2, Gap junction protein, beta 6

Gene ID: 10804

NCBI Accession: NP_006774

UniProt: O95452

Pathways: Sensory Perception of Sound