Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN614766

Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibody (PE)

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms
UVO, CDHE, ECAD, LCAM, Arc-1, CD324, arc-1, cd324, cdhe, ecad, lcam, uvo, AA960649, E-cad, Ecad, L-CAM, Um, E-cadherin, E-Cad, XB-cadherin, XBcad, XTCAD-1, b-cadherin, cadherin-1, cdh1-a, cdhc-A, cdhp ... show more
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
Application
»Alternatives Flow Cytometry (FACS)
Pubmed 12 references available
Catalog no. ABIN614766
Quantity 100 tests
Price
401.50 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 6 to 8 Business Days
Immunogen T-47D cells
Clone 67A4
Isotype IgG1
Specificity This antibody 67A4 recognizes CD324 / E-cadherin, an approximately 100 kDa epithelial cell adhesion molecule, whose detection is important for determination of invasive potential of epithelial neoplasms.
Alternative Name CD324 / Cadherin-1
Background CD324 / E-cadherin is an epithelial cell surface molecule, which provides calcium- dependent homophilic interactions with E-cadherin of another cell. These intaractions take part in morphogenetic programs controlling the maintenance of the structural and functional integrity of epithelia and affect invasive potential of epithelial neoplasms. CD324 / E-cadherin is implicated in cell growth and differentiation, cell recognition, and sorting during developmental morphogenesis, as well as in aggregation-dependent cell survival. CD324 / E-cadherin-mediated cell adhesion system is highly regulated from inside the cell by a number of intracellular signaling pathways.
Alternate names: CAM 120/80, CDH1, CDHE, E-cadherin, Epithelial cadherin, UVO, Uvomorulin
Gene ID 999
NCBI Accession 9606
UniProt P12830
Research Area Extracellular Matrix, Signaling, Cytoskeleton
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA)
Preservative Sodium azide
Handling Advice DO NOT FREEZE! This product is photosensitive and should be protected from light.
Storage 4 °C
Expiry Date 12 months
Background publications Takeichi: "Cadherin cell adhesion receptors as a morphogenetic regulator." in: Science (New York, N.Y.), Vol. 251, Issue 5000, pp. 1451-5, 1991 (PubMed).

Armeanu, Bühring, Reuss-Borst et al.: "E-cadherin is functionally involved in the maturation of the erythroid lineage." in: The Journal of cell biology, Vol. 131, Issue 1, pp. 243-9, 1995 (PubMed).

Bühring, Müller, Herbst et al.: "The adhesion molecule E-cadherin and a surface antigen recognized by the antibody 9C4 are selectively expressed on erythroid cells of defined maturational stages." in: Leukemia, Vol. 10, Issue 1, pp. 106-16, 1996 (PubMed).

Pece, Chiariello, Murga et al.: "Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex." in: The Journal of biological chemistry, Vol. 274, Issue 27, pp. 19347-51, 1999 (PubMed).

Servet-Delprat, Vidalain, Bausinger et al.: "Measles virus induces abnormal differentiation of CD40 ligand-activated human dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 4, pp. 1753-60, 2000 (PubMed).

Pece, Gutkind: "Signaling from E-cadherins to the MAPK pathway by the recruitment and activation of epidermal growth factor receptors upon cell-cell contact formation." in: The Journal of biological chemistry, Vol. 275, Issue 52, pp. 41227-33, 2001 (PubMed).

Novak, Kraft, Haberstok et al.: "A reducing microenvironment leads to the generation of FcepsilonRIhigh inflammatory dendritic epidermal cells (IDEC)." in: The Journal of investigative dermatology, Vol. 119, Issue 4, pp. 842-9, 2002 (PubMed).

Kutlesa, Wessels, Speiser et al.: "E-cadherin-mediated interactions of thymic epithelial cells with CD103+ thymocytes lead to enhanced thymocyte cell proliferation." in: Journal of cell science, Vol. 115, Issue Pt 23, pp. 4505-15, 2002 (PubMed).

Robertson, Ali, McDonnell et al.: "Chronic renal allograft dysfunction: the role of T cell-mediated tubular epithelial to mesenchymal cell transition." in: Journal of the American Society of Nephrology : JASN, Vol. 15, Issue 2, pp. 390-7, 2004 (PubMed).

Furio, Guezennec, Ducarre et al.: "Differential effects of allergens and irritants on early differentiating monocyte-derived dendritic cells." in: European journal of dermatology : EJD, Vol. 18, Issue 2, pp. 141-7, 2008 (PubMed).

Caberg, Hubert, Begon et al.: "Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytes." in: Carcinogenesis, Vol. 29, Issue 7, pp. 1441-7, 2008 (PubMed).

Lin, Liao, Lee et al.: "Molecular events associated with epithelial to mesenchymal transition of nasopharyngeal carcinoma cells in the absence of Epstein-Barr virus genome." in: Journal of biomedical science, Vol. 16, pp. 105, 2009 (PubMed).

Alternatives for antigen "Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1)", type "Antibodies"
Hosts (131), (122), (9), (5), (4)
Reactivities (238), (83), (55), (34), (34), (24), (20), (19), (15), (14), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applications (177), (77), (61), (59), (43), (34), (31), (31), (31), (26), (12), (8), (6), (3), (2), (1), (1), (1)
Conjugates (10), (7), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Epitopes (11), (9), (8), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Beacon