anti-Human TNFRSF12A antibody for Enzyme Immunoassay

Recommended TNFRSF12A Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) Antibodies
  • CD266
  • FN14
  • TWEAKR
  • AI255180
  • C87282
  • Fn14
  • HPIP
  • TWEAK-R
  • TweakR
  • tumor necrosis factor receptor superfamily, member 12A
  • tumor necrosis factor receptor superfamily, member 12a
  • TNFRSF12A
  • Tnfrsf12a
Reactivity
Human
93
59
30
3
3
2
2
2
2
1
1
1
Host
Rabbit
50
42
8
3
Clonality
Polyclonal
Conjugate
This TNFRSF12A antibody is un-conjugated
11
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
53
49
20
16
16
14
13
12
3
3
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN5554803
$ 375.38
Plus shipping costs $45.00

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) Antibodies
Reactivity Human
(93), (59), (30), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Host Rabbit
(50), (42), (8), (3)
Clonality
Polyclonal
Conjugate This TNFRSF12A antibody is un-conjugated
(11), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(53), (49), (20), (16), (16), (14), (13), (12), (3), (3), (2), (1), (1), (1), (1), (1), (1)
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Product Details anti-TNFRSF12A Antibody

Target Details TNFRSF12A Application Details Handling Images
Specificity This antibody reacts to Fn14.
Purification Affinity chromatography purified via peptide column
Immunogen Fn14 antibody was raised against a human IgG1 Fc-tagged Fn14 protein.
Isotype IgG

Target Details TNFRSF12A

Product Details anti-TNFRSF12A Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD266 / TweakR (TNFRSF12A Antibody Abstract)
Background TWEAK is a TNF family member produced by IFN-gamma-stimulated monocytes and induces multiple cell death pathways including caspase-dependent apoptosis and cathepsin B-dependent necrosis. These pathways are mediated by the binding of TWEAK by fibroblast growth factor 14 (Fn14), a member of the TNF receptor superfamily. Yeast two-hybrid experiments have shown that FN14 will bind to the TNFR-associated factors TRAF1, TRAF2, TRAF3, and TRAF5, suggesting that the signaling pathway induced by TWEAK may be mediated by one or more of these adaptor molecules. Fn14 is induced during liver regeneration and is highly expressed in hepatocellular carcinomas. In addition, TWEAK induces liver progenitor cell proliferation, suggesting Fn14 may play a role in hepatocyte growth control and liver neoplasia.Synonyms: FGF-inducible 14, FN14, Fibroblast growth factor-inducible immediate-early response protein 14, TNFRSF12A, Tumor necrosis factor receptor superfamily member 12A, Tweak receptor
Gene ID 51330
NCBI Accession NP_057723
UniProt Q9NP84
Research Area Receptors
Pathways Apoptosis, Regulation of Cell Size

Application Details

Product Details anti-TNFRSF12A Antibody Target Details TNFRSF12A Handling Images back to top
Application Notes ELISA. Western BLot: 2-4 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF12A Antibody Target Details TNFRSF12A Application Details Images back to top
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.