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Browse our anti-ACTN3 (ACTN3) Antibodies

Full name:
anti-Actinin, alpha 3 Antibodies (ACTN3)
On www.antibodies-online.com are 53 Actinin, alpha 3 (ACTN3) Antibodies from 16 different suppliers available. Additionally we are shipping ACTN3 Kits (28) and ACTN3 Proteins (3) and many more products for this protein. A total of 88 ACTN3 products are currently listed.
Synonyms:
acta-3, CG8953, dabp, Dmel\\CG8953, ORF1
list all antibodies Gene Name GeneID UniProt
ACTN3 11474 O88990
ACTN3 171009  
ACTN3 89 Q08043

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Most Popular Reactivities for anti-ACTN3 (ACTN3) Antibodies

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anti-Mouse (Murine) ACTN3 Antibodies:

anti-Rat (Rattus) ACTN3 Antibodies:

anti-Human ACTN3 Antibodies:

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Top referenced anti-ACTN3 Antibodies

  1. Human Polyclonal ACTN3 Primary Antibody for EIA, WB - ABIN950371 : Rodríguez-Romo, Ruiz, Santiago, Fiuza-Luces, González-Freire, Gómez-Gallego, Morán, Lucia: Does the ACE I/D polymorphism, alone or in combination with the ACTN3 R577X polymorphism, influence muscle power phenotypes in young, non-athletic adults? in European journal of applied physiology 2010 (PubMed)
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More Antibodies against ACTN3 Interaction Partners

Horse (Equine) Actinin, alpha 3 (ACTN3) interaction partners

  1. The ACTN3 gene is 13.2 kb long and contains 21 exons. The equine ACTN3 gene has a ubiquitous expression but it is overexpressed in skeletal muscles

Mouse (Murine) Actinin, alpha 3 (ACTN3) interaction partners

  1. Actn3 controls sarcomeric composition and muscle function in a dose-dependent fashion.

  2. New insights that have been made in understanding the molecular mechanisms that underlie the consequences of alpha-actinin-3 deficiency.[review]

  3. Absence of alpha-actinin-3 resulted in reduced atrophic response and altered adaptation to disuse, as measured by a change in myosin heavy chain isoform.

  4. ACTN3 likely contributes to the regulation of bone mass through alterations in bone turnover.

  5. Data demonstrated that the Z-disk proteins, ZASP (show LDB3 Antibodies), titin (show TTN Antibodies) and vinculin (show VCL Antibodies) preferentially bind to alpha-actinin-2 (show ACTN2 Antibodies). Thus, the loss of alpha-actinin-3 changes the overall protein composition of fast fiber Z-disks and alters their elastic properties.

  6. Actn3 knockout mice showed differences in intrinsic exercise performance, fast muscle force generation and male muscle mass.

  7. alpha-actinin-3 may play a role in the development of fast-twitch, glycolytic properties in a muscle fiber, and in its absence slower twitch, more oxidative properties may develop.

  8. alpha-Actinin-3 deficiency reduces the activity of glycogen (show GYS1 Antibodies) phosphorylase and results in a fundamental shift toward more oxidative pathways of energy utilization--REVIEW

  9. alpha-actinin-3 expression in a knockout mouse model results in a shift in muscle metabolism toward the more efficient aerobic pathway and an increase in intrinsic endurance performance

  10. Study reports that muscle from Actn3 knockout mice displays reduced force generation, consistent with results from human association studies.

Human Actinin, alpha 3 (ACTN3) interaction partners

  1. our data showed a virtual absence of the variant (K) allele in MSTN (show MSTN Antibodies) rs1805086 in Japanese population, and no differences in allele/genotype frequencies in ACTN3 rs1815739 among centenarians and healthy controls of this country.

  2. Results indicate that the posthemorrhagic shock mesenteric lymph in vitro increases the cellular permeability of human umbilical vein endothelial cells through suppression of F-actin and VE-cadherin (show CDH5 Antibodies).

  3. These findings provide the basis for further functional investigations of the ITSN/CR16 complex that may play an important role in actin remodeling and cellular invasion.

  4. The elite soccer players showed a tendency to a prevalence of ACTN3 RR and ACE (show ACE Antibodies) DD genotypes both independently and in co-occurrence, in comparison with a general population.

  5. the ACTN3 R577X polymorphism influences the level of competition and lower-extremity power of elite Chinese sprint/power athletes

  6. It appears that the response of bone remodelling markers and undercarboxylated osteocalcin (show BGLAP Antibodies) to exercise is not explained by the ACTN3 genotype

  7. We did not identify novel associations between physical activity and ACTN3.

  8. In comparison to RR homozygotes, X allele carriers for the R577X polymorphism of the ACTN3 gene presented higher values for typical markers of exercise-induced muscle damage during a competitive marathon.

  9. There was no statistically significant association between angiotensin-converting enzyme (show ACE Antibodies) or alpha-actinin-3 polymorphisms and the presence of adolescent idiopathic scoliosis in females.

  10. Study suggests that ACTN3 R577X polymorphism is associated with non-acute ankle sprain in the Chinese Han population.

Rabbit Actinin, alpha 3 (ACTN3) interaction partners

  1. examine the dynamics of actin in the presence of alpha-acinin in solution; suggest mechanisms to deny binding access to other actin-binding proteins and may explain how very different actin cytoskeletal structures may co-exist in the same cell

  2. Alpha-actinin may contribute to tension sensing in actin bundles.

ACTN3 Antigen Profile

Antigen Summary

This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants. The reference genome contains the non-coding allele. The non-functional allele of this gene is associated with elite athlete status.

Alternative names and synonyms associated with ACTN3

  • alpha actinin 3 (Actn3) antibody
  • actinin, alpha 3 (actn3) antibody
  • actinin, alpha 3 (ACTN3) antibody
  • actinin alpha 3 (Actn3) antibody
  • actinin, alpha 3 (Actn3) antibody
  • acta-3 antibody
  • CG8953 antibody
  • dabp antibody
  • Dmel\\CG8953 antibody
  • ORF1 antibody

Protein level used designations for ACTN3

Actn3-PA , CG8953-PA , alpha-actinin-like , alpha-actinin3 , open reading frame 1 , actinin, alpha 3 , alpha-actinin-3 , alpha 3 actinin , alpha-actinin-3-like , F-actin cross-linking protein , alpha-actinin skeletal muscle , muscle alpha-actinin subunit

GENE ID SPECIES
44964 Drosophila melanogaster
446326 Xenopus laevis
713811 Macaca mulatta
100033871 Equus caballus
100216053 Xenopus (Silurana) tropicalis
100439754 Pongo abelii
11474 Mus musculus
171009 Rattus norvegicus
89 Homo sapiens
100009544 Oryctolagus cuniculus
100730348 Cavia porcellus
539375 Bos taurus
483707 Canis lupus familiaris
101115917 Ovis aries
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