Browse our anti-Polymerase (DNA Directed), mu (POLM) Antibodies

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anti-Polymerase (DNA Directed), mu Antibodies (POLM)
On are 38 Polymerase (DNA Directed), mu (POLM) Antibodies from 12 different suppliers available. Additionally we are shipping Polymerase (DNA Directed), mu Proteins (2) and many more products for this protein. A total of 43 Polymerase (DNA Directed), mu products are currently listed.
AI462166, B230309I03Rik, POLM, Pol Mu, polmu, Tdt-N, zgc:56122
list all antibodies Gene Name GeneID UniProt
POLM 27434 Q9NP87
POLM 54125 Q9JIW4
POLM 289757  

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Top referenced anti-Polymerase (DNA Directed), mu Antibodies

  1. Cow (Bovine) Polyclonal POLM Primary Antibody for WB - ABIN2785958 : Juárez, Ruiz, Nick McElhinny, Ramsden, Blanco: A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis. in Nucleic acids research 2006 (PubMed)

More Antibodies against Polymerase (DNA Directed), mu Interaction Partners

Zebrafish Polymerase (DNA Directed), mu (POLM) interaction partners

  1. Polmicro expression was detected not only in pro- and mesonephros, the major sites for B-lymphocyte (show AKAP17A Antibodies) development, but also in ovary and testis and in all tissue preparations to a low extent.

Human Polymerase (DNA Directed), mu (POLM) interaction partners

  1. analysis of template-dependent synthesis by human polymerase mu

  2. A study of how Polmu fixes and/or orients the mobile Loop1 part of the protein in accordance with the substrate on which it is polymerizing.

  3. specific loop 1 residues contribute to Pol mu's unique ability to catalyze template-dependent NHEJ of DSBs with unpaired 3' ends

  4. evidence suggests that Polmu could be regulated in vivo by phosphorylation of the BRCT domain (Ser12/Thr21) and of Ser372, affecting the function of loop1; Polmu's most distinctive activities would be turned off at specific cell-cycle phases (S and G2), when these functions might be harmful to the cell

  5. A specific N-terminal extension of the 8 kDa domain of DNA polymerase mu is potentially implicated in the maintenance of a closed conformation throughout the catalytic cycle, and this study indicated that it could be a target of Cdk (show CDK4 Antibodies) phosphorylation.

  6. The study points at human Polmicro residues His(329) and Arg(387) as responsible for regulating nucleotide expansions occurring during DNA repair transactions, either promoting or blocking, respectively, iterative polymerization.

  7. Pol mu binds to DNA through its amino-terminal and pol beta (show POLB Antibodies)-like regions.

  8. DNA polymerase mu performs DNA synthesis at a AAF lesion

  9. Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair.

  10. DNA polymerase mu acts in response to several types of DNA damage with a lesion bypass mechanism

Mouse (Murine) Polymerase (DNA Directed), mu (POLM) interaction partners

  1. A role for PolMU in the prevention of sarcomagenesis on a murine P53 (show TP53 Antibodies)-deficient background was identified.

  2. Pol mu and Pol lambda (show POLL Antibodies) play a key role in conferring on NHEJ the flexibility required for accurate and efficient repair

  3. Polmu deficiency activates transcriptional networks that reduce constitutive apoptosis, leading to enhanced liver repair at old age.

  4. DNA polymerase mu has a role in decreased learning and brain long-term potentiation in aged mice

  5. These data point to a critical role for pol mu as a global repair player that increases the efficiency and the fidelity of non-homologous end-joining.

  6. A series of molecular-dynamics simulations with and without the incoming nucleotide in various forms, including mutant systems, based on pol mu's crystal ternary structure, were analyzed.

  7. Pol mu is not required for normal Ig gene hypermutation.

  8. Pol mu promotes accuracy during Ig kappa recombination.

  9. third hypervariable region assumes for each immunoglobulin chain, with pol lambda (show POLL Antibodies) maintaining a large heavy chain junctional heterogeneity and pol mu ensuring a restricted light chain junctional variability

  10. The crystal structure of the polymerase domain of murine Pol mu bound to gapped DNA with a correct dNTP at the active site reveals substrate interactions with side chains in Pol mu that differ from other family X members.

Polymerase (DNA Directed), mu (POLM) Antigen Profile

Antigen Summary

Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.

Alternative names and synonyms associated with Polymerase (DNA Directed), mu (POLM)

  • polymerase (DNA directed), mu (polm) antibody
  • polymerase (DNA directed), mu (POLM) antibody
  • DNA polymerase mu (CC1G_09351) antibody
  • DNA polymerase mu (VDBG_09335) antibody
  • polymerase (DNA directed), mu (Polm) antibody
  • AI462166 antibody
  • B230309I03Rik antibody
  • POLM antibody
  • Pol Mu antibody
  • polmu antibody
  • Tdt-N antibody
  • zgc:56122 antibody

Protein level used designations for POLM

DNA polymerase mu , DNA-directed DNA polymerase mu , DNA-directed DNA/RNA polymerase mu , polymerase (DNA directed), mu , DNA polymerase mu-like , Pol iota , polymerase (DNA-directed), mu , terminal transferase , pol Mu

393218 Danio rerio
513780 Bos taurus
737708 Pan troglodytes
100461859 Pongo abelii
100515113 Sus scrofa
100590644 Nomascus leucogenys
6006630 Coprinopsis cinerea okayama7130
9528971 Verticillium alfalfae VaMs.102
27434 Homo sapiens
54125 Mus musculus
289757 Rattus norvegicus
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