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Browse our anti-Methyl CpG Binding Protein 2 (Rett Syndrome) (MECP2) Antibodies

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anti-Methyl CpG Binding Protein 2 (Rett Syndrome) Antibodies (MECP2)
On www.antibodies-online.com are 0 Methyl CpG Binding Protein 2 (Rett Syndrome) (MECP2) Antibodies from different suppliers available. A total of 0 Methyl CpG Binding Protein 2 (Rett Syndrome) products are currently listed.
Synonyms:
1500041B07Rik, AUTSX3, BB130002, D630021H01Rik, Mbd5, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT, WBP10, wu:fk96a04, zgc:111857
list all antibodies Gene Name GeneID UniProt
Anti-Mouse MECP2 MECP2 17257 Q9Z2D6
Anti-Rat MECP2 MECP2 29386 Q00566
Anti-Human MECP2 MECP2 4204 P51608

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More Antibodies against Methyl CpG Binding Protein 2 (Rett Syndrome) Interaction Partners

Zebrafish Methyl CpG Binding Protein 2 (Rett Syndrome) (MECP2) interaction partners

  1. A mecp2-null allele mutation zebrafish model is developed and the animals are viable and fertile.

Mouse (Murine) Methyl CpG Binding Protein 2 (Rett Syndrome) (MECP2) interaction partners

  1. Mecp2 is responsive to neuronal stimulation and IGF1 (show IGF1 Antibodies), and different stimuli have different effects on Mecp2 expression; this differential response may have downstream effects on functional mechanisms regulating brain development and plasticity.

  2. MeCP2 binding to chromosomal DNA in mouse brain is proportional to mCAC (show SLC25A20 Antibodies) + mCG density.

  3. Results confirm and extend earlier published findings that specific aspects of cholesterol metabolism in the CNS, particularly the biosynthetic pathway, are disrupted in mouse models with loss-of-function mutations in Mecp2

  4. Repression of TSC1 (show TSC1 Antibodies)/TSC2 (show TSC2 Antibodies) mediated by MeCP2 regulates human embryo lung fibroblast cell differentiation and proliferation.

  5. Data suggest that newborn Mecp2 null cortical neurons display critical transcriptional defects that lead to reduced neuronal responsiveness, which, in turn, delays and disrupts proper neuronal maturation

  6. absence leads to decreased cortical levels of the GAT-1 GABA transporter, facilitating cortical network hyper-excitability by increasing the activity of cortical GABAB receptors

  7. Knockdown of methyl-CpG-binding protein (show CXXC1 Antibodies) leads to upregulation of microRNA-137, which in turn represses expression of PTEN (show PTEN Antibodies) protein.

  8. Study demonstrates that the time course of N-methyl-D-aspartate receptor (show GRIN1 Antibodies) maturation is cell-type specific, and a new cell-type specific role for Mecp2 in the development of -methyl-D-aspartate receptor subunit composition.

  9. Data highlight functional hypoconnectivity in the medial prefrontal cortex as a potential substrate for behavioral disruption in Rett syndrome and other disorders associated with reduced expression of Mecp2 in frontal cortical regions.

  10. These findings indicate that tongue heat sensitivity and hypersensitivity are dependent on the expression of transient receptor potential vanilloid 1 which is regulated via MeCP2 signaling in trigeminal ganglion neurons innervating the tongue.

Human Methyl CpG Binding Protein 2 (Rett Syndrome) (MECP2) interaction partners

  1. we could not find any significant correlation between specific MECP2 mutations and individual clinical features or global clinical score in Rett syndrome patients

  2. findings demonstrate clear phenotype differences between FOXG1 (show FOXG1 Antibodies) and MECP2 disorders.

  3. Binding cooperativity makes MeCP2 an effective competitor with histone H1 (show H1F0 Antibodies) for accessible DNA sites. The relationship between MeCP2 binding specificity and cooperativity is discussed in the context of chromatin binding, neuronal function, and neuronal development.

  4. Our data indicate that these motifs are secondary contributors to DNA binding by MeCP2, and this view is supported by the absence of disease-causing missense mutations at these sites

  5. Six patients (5 females and 1 male) with intellectual disability and present with some Rett syndrome features showed missense methyl-CpG binding protein 2 (MECP2) variants.

  6. Repression of TSC1 (show TSC1 Antibodies)/TSC2 (show TSC2 Antibodies) mediated by MeCP2 regulates human embryo lung fibroblast cell differentiation and proliferation.

  7. This study demonstrated that the MECP2 duplication of Autism showed that spine pathology in brain.

  8. Our findings confirm a high mutation frequency in classic RTT (92%) and a correlation between the MECP2 mutation type and clinical severity. We also demonstrate limitations of XCI in explaining all of the phenotypic differences in RTT.

  9. Data show that MeCP2 promotes gastric cancer (GC) cell proliferation via FOXF1 (show FOXF1 Antibodies)-mediated Wnt5a (show WNT5A Antibodies)/beta-Catenin (show CTNNB1 Antibodies) signaling pathway, and suppresses GC cell apoptosis through MYOD1 (show MYOD1 Antibodies)-mediated Caspase-3 (show CASP3 Antibodies) signaling pathway.

  10. To our knowledge, we describe the first association between MECP2 mutation, chromosomal abnormalities and high sister-chromatid exchange frequency

Methyl CpG Binding Protein 2 (Rett Syndrome) (MECP2) Antigen Profile

Antigen Summary

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.

Alternative names and synonyms associated with Methyl CpG Binding Protein 2 (Rett Syndrome) (MECP2)

  • methyl CpG binding protein 2 (mecp2) antibody
  • methyl CpG binding protein 2 (Mecp2) antibody
  • methyl CpG binding protein 2 (Rett syndrome) (MECP2) antibody
  • methyl CpG binding protein 2 (Rett syndrome) (mecp2) antibody
  • 1500041B07Rik antibody
  • AUTSX3 antibody
  • BB130002 antibody
  • D630021H01Rik antibody
  • Mbd5 antibody
  • MRX16 antibody
  • MRX79 antibody
  • MRXS13 antibody
  • MRXSL antibody
  • PPMX antibody
  • RS antibody
  • RTS antibody
  • RTT antibody
  • WBP10 antibody
  • wu:fk96a04 antibody
  • zgc:111857 antibody

Protein level used designations for MECP2

methyl-CpG-binding protein 2 , meCp-2 protein , meCP-2 protein , methyl-CpG-binding protein MeCP2

GENE ID SPECIES
335250 Danio rerio
17257 Mus musculus
29386 Rattus norvegicus
4204 Homo sapiens
612973 Canis lupus familiaris
100328751 Oryctolagus cuniculus
398087 Xenopus laevis
539629 Bos taurus
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