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anti-Rat (Rattus) MAP2K7 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MAP2K7 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) Antibodies
  • 2
  • 5930412N11Rik
  • JNKK
  • JNKK 2
  • Jnkk2
  • MAP2K7
  • map2k7-A
  • MAPKK 7
  • MAPKK7
  • Mapkk7
  • MEK 7
  • Mek7
  • MKK7
  • Mkk7
  • Prkmk7
  • PRKMK7
  • SAPKK-4
  • SAPKK4
  • sek2
  • si:ch211-254d18.2
Epitope
AA 2-40, N-Term
29
27
20
15
13
9
7
5
5
5
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
125
60
50
1
1
1
Host
Rabbit
111
22
Clonality
Polyclonal
Conjugate
This MAP2K7 antibody is un-conjugated
5
5
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
113
69
45
16
13
11
9
6
5
3
2
1
1
Supplier
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Catalog No. ABIN3043875
$ 240.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008982679 ABIN189534 ICC FACS IF IHC (p) IP IHC WB Rabbit IgG C-Term Log in to see EP1455Y
0.0008982679 ABIN743927 IHC (p) WB HRP Rabbit IgG pSer271, pThr275 Log in to see Polyclonal
0.0008982679 ABIN743920 IHC (p) WB Biotin Rabbit IgG pSer271, pThr275 Log in to see Polyclonal
0.0008982679 ABIN743918 IF (p) IHC (p) WB Rabbit IgG pSer271, pThr275 Log in to see Polyclonal

Similar anti-MAP2K7 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 110 Antibodies 48 Antibodies 42 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 6 Antibodies 4 Antibodies 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 13 Antibodies 8 Antibodies 5 Antibodies
Immunohistochemistry (IHC) 45 Antibodies 20 Antibodies 18 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies 2 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies 11 Antibodies
Immunofluorescence (IF) 17 Antibodies

General

Antigen Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) Antibodies
Epitope AA 2-40, N-Term
(29), (27), (20), (15), (13), (9), (7), (5), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(125), (60), (50), (1), (1), (1)
Host Rabbit
(111), (22)
Clonality
Polyclonal
Conjugate This MAP2K7 antibody is un-conjugated
(5), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(113), (69), (45), (16), (13), (11), (9), (6), (5), (3), (2), (1), (1)
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Product Details anti-MAP2K7 Antibody

Target Details MAP2K7 Application Details Handling Images
Sequence AASSLEQKLS RLEAKLKQEN REARRRIDLN LDISPQRPR
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Dual specificity mitogen-activated protein kinase kinase 7(MAP2K7) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: mitogen-activated protein kinase kinase 7
Protein Name: Dual specificity mitogen-activated protein kinase kinase 7
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human MEK7 (2-40aa AASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPR), identical to the related mouse and rat sequences.
Isotype IgG

Target Details MAP2K7

Product Details anti-MAP2K7 Antibody Application Details Handling Images back to top
Antigen
Alternative Name MAP2K7 (MAP2K7 Antibody Abstract)
Background MAP2K7(Mitogen-activated protein kinase kinase 7), also known as MAP kinase kinase 7, MAPKK7, JNKK2, PRKMK7 or MKK7, is an enzyme that in humans is encoded by the MAP2K7 gene. This protein is a member of the mitogen-activated protein kinase kinase family. The MKK7 protein exists as six different isoforms with three possible N-termini (α, β, and γ isoforms) and two possible C-termini (1 and 2 isoforms). Schramek et al. (2011) showed that the doxorubicin-mediated DNA damage response in human A549 lung carcinoma cells caused rapid phosphorylation and upregulation of p53 (TP53). MKK7 knockdown reduced p53 phosphorylation, delayed p53 upregulation, and interfered with cell cycle arrest at G2/M. MKK7 was activated in primary lung tumors, and tumors with a p53 mutation showed even higher MKK7 phosphorylation. Schramek et al. (2011) concluded that MKK7 exerts its tumor suppressive function through p53.
Gene ID 5609
UniProt O14733
Research Area Kinases/Phosphatases
Pathways MAPK Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-MAP2K7 Antibody Target Details MAP2K7 Handling Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions For Research Use only

Handling

Product Details anti-MAP2K7 Antibody Target Details MAP2K7 Application Details Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C,4 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Images

Product Details anti-MAP2K7 Antibody Target Details MAP2K7 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-MAP2K7 antibody (Mitogen-Activated Protein Kinase Kinase 7) (AA 2-40) (ABIN3043875) IHC(P): Human Intestinal Cancer Tissue
Immunohistochemistry (IHC) image for anti-MAP2K7 antibody (Mitogen-Activated Protein Kinase Kinase 7) (AA 2-40) (ABIN3043875) IHC(P): Rat Lung Tissue
Western Blotting (WB) image for anti-MAP2K7 antibody (Mitogen-Activated Protein Kinase Kinase 7) (AA 2-40) (ABIN3043875) anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (AA 2-40), (N-Term) antibody (Image 3)
Immunohistochemistry (IHC) image for anti-MAP2K7 antibody (Mitogen-Activated Protein Kinase Kinase 7) (AA 2-40) (ABIN3043875) IHC(P): Mouse Lung Tissue