anti-Mouse (Murine) IRAK1 antibody for Enzyme Immunoassay

Recommended IRAK1 Antibody (supplied by: Log in to see )

Antigen
Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) Antibodies
  • IRAK1
  • IRAK
  • pelle
  • AA408924
  • IRAK-1
  • IRAK1-S
  • Il1rak
  • Plpk
  • mPLK
  • RGD1563841
  • interleukin 1 receptor associated kinase 1
  • interleukin-1 receptor-associated kinase 1
  • IRAK1
  • irak1
  • Irak1
Epitope
C-Term
42
33
24
23
19
15
15
15
15
13
11
9
8
8
8
7
5
5
5
5
4
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
251
128
95
2
1
1
Host
Rabbit
240
43
2
Clonality
Polyclonal
Conjugate
This IRAK1 antibody is un-conjugated
12
11
10
6
6
6
4
4
4
4
4
4
4
4
4
4
4
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
200
130
70
54
52
42
35
17
16
9
7
3
1
1
Supplier
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Catalog No. ABIN5554895
$ 469.32
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN303104 EIA IHC (p) IP WB Rabbit Log in to see Polyclonal
1 ABIN5551058 EIA IHC (p) WB Mouse IgG AA 618-712 Log in to see 1F12C1
1 ABIN5551059 EIA IHC (p) WB Mouse IgG AA 618-712 Log in to see 8F1A7

General

Antigen Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) Antibodies
Epitope C-Term
(42), (33), (24), (23), (19), (15), (15), (15), (15), (13), (11), (9), (8), (8), (8), (7), (5), (5), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(251), (128), (95), (2), (1), (1)
Host Rabbit
(240), (43), (2)
Clonality
Polyclonal
Conjugate This IRAK1 antibody is un-conjugated
(12), (11), (10), (6), (6), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(200), (130), (70), (54), (52), (42), (35), (17), (16), (9), (7), (3), (1), (1)
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Product Details anti-IRAK1 Antibody

Target Details IRAK1 Application Details Handling Images
Specificity IRAK antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human IRAK.
Purification DEAE
Immunogen Human IRAK (C-Terminus) Peptide
Isotype IgG

Target Details IRAK1

Product Details anti-IRAK1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name IRAK1 (IRAK1 Antibody Abstract)
Background Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-kappaB activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).Synonyms: IRAK, IRAK-1, Interleukin-1 receptor-associated kinase 1
Gene ID 3654
UniProt P51617
Research Area Cytokines, Inflammation, Receptors
Pathways NF-kappaB Signaling, TLR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Application Details

Product Details anti-IRAK1 Antibody Target Details IRAK1 Handling Images back to top
Application Notes ELISA. Western Blot: 1/1000. Immunocytochemistry. Immunoprecipitation: 2 to 4 μg per sample. An 80 kDa band should be detected in the lysate from non-activated cells. It has no crossresponse to IRAK2.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IRAK1 Antibody Target Details IRAK1 Application Details Images back to top
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.