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Browse our anti-POLR2A (POLR2A) Antibodies

Full name:
anti-Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa Antibodies (POLR2A)
On www.antibodies-online.com are 56 Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa (POLR2A) Antibodies from 15 different suppliers available. Additionally we are shipping POLR2A Kits (6) and POLR2A Proteins (2) and many more products for this protein. A total of 65 POLR2A products are currently listed.
Synonyms:
19.m02399, 220kDa, hRPB220, hsRPB1, NCU02103.1, POLR2, POLR2A, POLRA, RPB1, RPBh1, RpIILS, RPO2, Rpo2-1, RPOL2
list all antibodies Gene Name GeneID UniProt
POLR2A 20020 P08775
POLR2A 363633  
POLR2A 5430 P24928

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Most Popular Reactivities for anti-POLR2A (POLR2A) Antibodies

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anti-Mouse (Murine) POLR2A Antibodies:

anti-Rat (Rattus) POLR2A Antibodies:

anti-Human POLR2A Antibodies:

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Top referenced anti-POLR2A Antibodies

  1. Fruit Fly (Drosophila melanogaster) Monoclonal POLR2A Primary Antibody for IHC (fro), IF - ABIN125963 : Lipsky, Abramson, Breedveld, Brook, Burmester, Buttgereit, Cannon, Catella-Lawson, Crofford, Doherty, Dougados, DuBois, Froelich, Garcia Rodriguez, Gibofsky, Hernandez-Diaz, Hochberg, Krause, Liang, Machold, Peloso, Raisz, Schayes, Scheiman, Simon, Smolen: Analysis of the effect of COX-2 specific inhibitors and recommendations for their use in clinical practice. in The Journal of rheumatology 2000 (PubMed)
    Show all 6 references for ABIN125963

More Antibodies against POLR2A Interaction Partners

Mouse (Murine) Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa (POLR2A) interaction partners

  1. An H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation.

  2. Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription

  3. These data indicate that, through cooperation with PolII and KDM6A (show KDM6A Antibodies), Spt6 (show SUPT6H Antibodies) orchestrates removal of H3K27me3, thus controlling developmental gene expression and cell differentiation.

  4. site-specific p65 phosphorylation targets NF-kappaB activity to particular gene subsets on a global level by influencing p65 and p-RNAP II promoter recruitment

  5. Data show that that B2 RNA, when present with Pol II in promoter-bound complexes, specifically represses CTD phosphorylation by TFIIH (show GTF2H4 Antibodies).

  6. investigation of contribution of largest subunit of phosphorylated RNAP II to onset of minor gene activation in zygote; nuclear localization of RNAP II in 1-cell zygote; regulation of RNAP II expression by deposition of acetylated histone on promoter

  7. involvement of RPB1, the largest subunit of RNA polymerase II (RNAP II), in the regulation of transcriptional silencing mechanism

  8. Reduction in RNA Pol II (show POLR2F Antibodies) association is indicative of interruption in direct interactions of RNA Pol II (show POLR2F Antibodies) with PEPCK (show PEPCK Antibodies) promoter, with general transcription factors and/or with coregulator molecules contributeing to activation of PEPCK (show PEPCK Antibodies) gene.

  9. These results indicate that Wwp2 plays an important role in regulating expression of Rpb1 in normal physiological conditions.[Rpb1]

  10. Results suggest that RNA polymerase II is selectively required for positive transcriptional regulation of a subset of genes in embryonic stem cells.

Human Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa (POLR2A) interaction partners

  1. HIV Tat precisely controls RNA polymerase II recruitment and pause release to fine-tune the initiation and elongation steps in target genes.

  2. TOP1 bound at promoters was discovered to become fully active only after pause-release. This transition coupled the phosphorylation of the carboxyl-terminal-domain (CTD) of RNA polymerase II (RNAPII) with stimulation of TOP1 above its basal rate, enhancing its processivity.

  3. Its variant is not related to sporadic PD in Chinese Han population.

  4. Data suggest RNA polymerase II (POLR2A) is extensively modified on its unique C-terminal domain (CTD) by O-GlcNAc (show OGT Antibodies) transferase (OGT (show OGT Antibodies)); efficient O-GlcNAcylation requires a minimum of 20 heptad CTD repeats in POLR2A and more than half of NTD of OGT (show OGT Antibodies).

  5. Serine phosphorylation stimulates whereas tyrosine phosphorylation inhibits the protein-binding activity of the RNA Pol II C-terminal domain.

  6. The amount of RNA polymerase II (RNAPII) on the HIV promoter and other viral regions was strongly diminished in HIV-infected CD4+ cells co-cultivated with cell non-cytotoxic antiviral response-expressing CD8+ cells.

  7. Ash2L acts in concert with P53 promoter occupancy to activate RNA Polymerase II by aiding formation of a stable transcription pre-initiation complex required for its activation.

  8. Data suggest that RNA polymerase II inhibitors may be a useful class of agent for targeting dormant leukaemia cells.

  9. This viral pre-initiation complex is composed of five different proteins in addition to Epstein-Barr virus BcRF1 and interacts with cellular RNA polymerase II

  10. Data show that E2F-1 (show E2F1 Antibodies) form a complex with RNA polymerase II and protein PURA (show PURA Antibodies) for transcriptional activation of the secondary promoter.

POLR2A Antigen Profile

Antigen Summary

This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

Alternative names and synonyms associated with POLR2A

  • DNA-directed RNA polymerase II largest subunit (NCU02103) antibody
  • DNA-directed RNA polymerase II largest subunit (BBOV_I003360) antibody
  • DNA-directed RNA polymerase II subunit RPB1 (EDI_169920) antibody
  • DNA-directed RNA polymerase II subunit RPB1 (CMU_000800) antibody
  • DNA-directed RNA polymerase II subunit RPB1 (SJAG_01713) antibody
  • DNA-directed RNA polymerase II subunit RPB1 (MGYG_01527) antibody
  • polymerase (RNA) II (DNA directed) polypeptide A, 220kDa (POLR2A) antibody
  • DNA-directed RNA polymerase II largest subunit (TP03_0185) antibody
  • DNA-directed RNA polymerase II largest subunit (EBI_22514) antibody
  • DNA-directed RNA polymerase II largest subunit (CGB_E5020W) antibody
  • polymerase (RNA) II (DNA directed) polypeptide A, 220kDa (polr2a) antibody
  • polymerase (RNA) II (DNA directed) polypeptide A (Polr2a) antibody
  • 19.m02399 antibody
  • 220kDa antibody
  • hRPB220 antibody
  • hsRPB1 antibody
  • NCU02103.1 antibody
  • POLR2 antibody
  • POLR2A antibody
  • POLRA antibody
  • RPB1 antibody
  • RPBh1 antibody
  • RpIILS antibody
  • RPO2 antibody
  • Rpo2-1 antibody
  • RPOL2 antibody

Protein level used designations for POLR2A

DNA-directed RNA polymerase II subunit RPB1 , polymerase (RNA) II (DNA directed) polypeptide A, 220kDa , 220 kDa DNA-directed RNA polymerase polypeptide A , DNA-directed RNA polymerase II largest subunit , RNA polymerase II polypeptide A , DNA-directed RNA polymerase II A , DNA-directed RNA polymerase II subunit A , DNA-directed RNA polymerase III largest subunit , RNA polymerase II 1 , RNA polymerase II subunit B1 , Polymerase (RNA II (DNA directed), large polypeptide , DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit , RNA-directed RNA polymerase II subunit RPB1 , polymerase (RNA) II (DNA directed) polypeptide A (220kD)

GENE ID SPECIES
3880246 Neurospora crassa OR74A
5477202 Babesia bovis T2Bo
5878979 Entamoeba dispar SAW760
6996694 Cryptosporidium muris RN66
7049878 Schizosaccharomyces japonicus yFS275
10032782 Arthroderma gypseum CBS 118893
454463 Pan troglodytes
479483 Canis lupus familiaris
721865 Macaca mulatta
3500122 Theileria parva strain Muguga
6004135 Enterocytozoon bieneusi H348
10189812 Cryptococcus gattii WM276
100014728 Monodelphis domestica
100144762 Ovis aries
100373197 Saccoglossus kowalevskii
100389642 Callithrix jacchus
100432084 Pongo abelii
100466109 Ailuropoda melanoleuca
100561860 Anolis carolinensis
100607400 Nomascus leucogenys
20020 Mus musculus
363633 Rattus norvegicus
5430 Homo sapiens
282312 Bos taurus
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