Browse our anti-POLR2A (POLR2A) Antibodies

Full name:
anti-Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa Antibodies (POLR2A)
On www.antibodies-online.com are 155 Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa (POLR2A) Antibodies from 17 different suppliers available. Additionally we are shipping POLR2A Kits (6) and POLR2A Proteins (2) and many more products for this protein. A total of 165 POLR2A products are currently listed.
Synonyms:
19.m02399, 220kDa, hRPB220, hsRPB1, NCU02103.1, POLR2, POLR2A, POLRA, RPB1, RPBh1, RpIILS, RPO2, Rpo2-1, RPOL2
list all antibodies Gene Name GeneID UniProt
POLR2A 20020 P08775
POLR2A 363633  
POLR2A 5430 P24928

Show all species

Show all synonyms

Most Popular Reactivities for anti-POLR2A (POLR2A) Antibodies

Select your species and application

anti-Mouse (Murine) POLR2A Antibodies:

anti-Rat (Rattus) POLR2A Antibodies:

anti-Human POLR2A Antibodies:

All available anti-POLR2A Antibodies

Go to our pre-filtered search.

Top referenced anti-POLR2A Antibodies

  1. Human Polyclonal POLR2A Primary Antibody for ICC, IF - ABIN4350645 : Nordick, Hoffman, Betz, Jaehning: Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II. in Eukaryotic cell 2008 (PubMed)
    Show all 11 references for 4350645

  2. Human Monoclonal POLR2A Primary Antibody for ChIP, CyTOF - ABIN268311 : Reid, Svejstrup: DNA damage-induced Def1-RNA polymerase II interaction and Def1 requirement for polymerase ubiquitylation in vitro. in The Journal of biological chemistry 2004 (PubMed)
    Show all 6 references for 268311

  3. Chicken Polyclonal POLR2A Primary Antibody for DB, WB - ABIN4350647 : Hsin, Sheth, Manley: RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3' end processing. in Science (New York, N.Y.) 2011 (PubMed)
    Show all 3 references for 4350647

More Antibodies against POLR2A Interaction Partners

Mouse (Murine) Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa (POLR2A) interaction partners

  1. An H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation.

  2. Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription

  3. These data indicate that, through cooperation with PolII and KDM6A (show KDM6A Antibodies), Spt6 (show SUPT6H Antibodies) orchestrates removal of H3K27me3, thus controlling developmental gene expression and cell differentiation.

  4. site-specific p65 phosphorylation targets NF-kappaB activity to particular gene subsets on a global level by influencing p65 and p-RNAP II promoter recruitment

  5. Data show that that B2 RNA, when present with Pol II in promoter-bound complexes, specifically represses CTD phosphorylation by TFIIH (show GTF2H4 Antibodies).

  6. investigation of contribution of largest subunit of phosphorylated RNAP II to onset of minor gene activation in zygote; nuclear localization of RNAP II in 1-cell zygote; regulation of RNAP II expression by deposition of acetylated histone on promoter

  7. involvement of RPB1, the largest subunit of RNA polymerase II (RNAP II), in the regulation of transcriptional silencing mechanism

  8. Reduction in RNA Pol II (show POLR2F Antibodies) association is indicative of interruption in direct interactions of RNA Pol II (show POLR2F Antibodies) with PEPCK (show PEPCK Antibodies) promoter, with general transcription factors and/or with coregulator molecules contributeing to activation of PEPCK (show PEPCK Antibodies) gene.

  9. These results indicate that Wwp2 plays an important role in regulating expression of Rpb1 in normal physiological conditions.[Rpb1]

  10. Results suggest that RNA polymerase II is selectively required for positive transcriptional regulation of a subset of genes in embryonic stem cells.

Human Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa (POLR2A) interaction partners

  1. Rpb1/2 dynamics help govern the decision between sense and divergent antisense transcription.

  2. The results showed heterogeneity in the responses of individual KSHV episomes to stimuli within a single reactivating cell; those episomes that did respond to stimulation, aggregated within large domains that appear to function as viral transcription factories. A significant portion of cellular RNA polymerase II was trapped in these factories and served to transcribe viral genomes.

  3. The authors show here that glutamine deprivation suppresses translation of endogenous MYC via coupling the 3'-UTR of the MYC mRNA and RNA polymerase II function.

  4. Data show that inhibition of VCP/p97, or siRNA-mediated ablation of VCP/p97 impairs ultraviolet radiation (UVR)-induced RNA polymerase II (RNAPII) degradation.

  5. Role of chromatin-bound EGFR and ERK kinases in RNA polymerase 2 transcription

  6. recurrent somatic mutations in POLR2A hijack this essential enzyme and drive meningioma neoplasia

  7. the Elongin A ubiquitin ligase and the CSB protein function together in a common pathway in response to Pol II stalling and DNA damage

  8. By studying global gene expression patterns and genome-wide DNA-binding patterns of CGGBP1 (show CGGBP1 Antibodies), it has been shown that a possible mechanism through which it affects the expression of RNA Pol II-transcribed genes in trans depends on Alu RNA.

  9. Using a 7,781-sample pan (show SUPT6H Antibodies)-cancer dataset, we first confirmed this in POLR2A are known to confer elevated sensitivity to pharmacological suppression.hese include the POLR2A interacting protein INTS10 (show INTS10 Antibodies) as well as genes involved in mRNA splicing, nonsense-mediated mRNA

  10. HIV Tat precisely controls RNA polymerase II recruitment and pause release to fine-tune the initiation and elongation steps in target genes.

POLR2A Antigen Profile

Antigen Summary

This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

Alternative names and synonyms associated with POLR2A

  • DNA-directed RNA polymerase II largest subunit (NCU02103) antibody
  • DNA-directed RNA polymerase II largest subunit (BBOV_I003360) antibody
  • DNA-directed RNA polymerase II subunit RPB1 (EDI_169920) antibody
  • DNA-directed RNA polymerase II subunit RPB1 (CMU_000800) antibody
  • DNA-directed RNA polymerase II subunit RPB1 (SJAG_01713) antibody
  • DNA-directed RNA polymerase II subunit RPB1 (MGYG_01527) antibody
  • polymerase (RNA) II (DNA directed) polypeptide A, 220kDa (POLR2A) antibody
  • DNA-directed RNA polymerase II largest subunit (TP03_0185) antibody
  • DNA-directed RNA polymerase II largest subunit (EBI_22514) antibody
  • DNA-directed RNA polymerase II largest subunit (CGB_E5020W) antibody
  • polymerase (RNA) II (DNA directed) polypeptide A, 220kDa (polr2a) antibody
  • polymerase (RNA) II (DNA directed) polypeptide A (Polr2a) antibody
  • 19.m02399 antibody
  • 220kDa antibody
  • hRPB220 antibody
  • hsRPB1 antibody
  • NCU02103.1 antibody
  • POLR2 antibody
  • POLR2A antibody
  • POLRA antibody
  • RPB1 antibody
  • RPBh1 antibody
  • RpIILS antibody
  • RPO2 antibody
  • Rpo2-1 antibody
  • RPOL2 antibody

Protein level used designations for POLR2A

DNA-directed RNA polymerase II subunit RPB1 , polymerase (RNA) II (DNA directed) polypeptide A, 220kDa , 220 kDa DNA-directed RNA polymerase polypeptide A , DNA-directed RNA polymerase II largest subunit , RNA polymerase II polypeptide A , DNA-directed RNA polymerase II A , DNA-directed RNA polymerase II subunit A , DNA-directed RNA polymerase III largest subunit , RNA polymerase II 1 , RNA polymerase II subunit B1 , Polymerase (RNA II (DNA directed), large polypeptide , DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit , RNA-directed RNA polymerase II subunit RPB1 , polymerase (RNA) II (DNA directed) polypeptide A (220kD)

GENE ID SPECIES
3880246 Neurospora crassa OR74A
5477202 Babesia bovis T2Bo
5878979 Entamoeba dispar SAW760
6996694 Cryptosporidium muris RN66
7049878 Schizosaccharomyces japonicus yFS275
10032782 Arthroderma gypseum CBS 118893
454463 Pan troglodytes
479483 Canis lupus familiaris
721865 Macaca mulatta
3500122 Theileria parva strain Muguga
6004135 Enterocytozoon bieneusi H348
10189812 Cryptococcus gattii WM276
100014728 Monodelphis domestica
100144762 Ovis aries
100373197 Saccoglossus kowalevskii
100389642 Callithrix jacchus
100432084 Pongo abelii
100466109 Ailuropoda melanoleuca
100561860 Anolis carolinensis
100607400 Nomascus leucogenys
20020 Mus musculus
363633 Rattus norvegicus
5430 Homo sapiens
282312 Bos taurus
Selected quality suppliers for anti-POLR2A (POLR2A) Antibodies
Did you look for something else?