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anti-Human TSC2 antibody for Dot Blot

Recommended TSC2 Antibody (supplied by: Log in to see )

Antigen
Tuberous Sclerosis 2 (TSC2) Antibodies
  • fc16b02
  • LAM
  • Nafld
  • Rc
  • Tcs2
  • TSC2
  • TSC4
  • tuberin
  • wu:fc16b02
Epitope
pSer1387
41
40
34
28
27
27
24
23
22
22
20
20
20
20
20
20
20
20
20
19
17
17
16
15
15
15
13
13
13
13
11
8
8
6
6
6
6
6
6
6
6
6
6
5
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
523
378
209
6
Host
Rabbit
697
24
Clonality
Polyclonal
Conjugate
This TSC2 antibody is un-conjugated
51
51
51
43
42
42
10
10
9
9
9
9
9
9
9
1
1
1
1
1
1
1
1
1
1
Application
Dot Blot (DB), Immunofluorescence (IF)
387
290
219
148
101
75
62
24
7
7
4
2
1
Supplier
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Catalog No. ABIN1881949
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.63784635 ABIN1881948 DB Rabbit pSer1388 Log in to see Polyclonal 3
0.63784635 ABIN1881947 DB Rabbit pSer1096 Log in to see Polyclonal 3
0.63784635 ABIN389800 DB IF Rabbit Ig pSer939 Log in to see Polyclonal
0.63784635 ABIN389817 DB IF Rabbit Ig pSer664 Log in to see Polyclonal
0.63784635 ABIN389864 DB IF Rabbit Ig pSer1420 Log in to see Polyclonal
0.63784635 ABIN389863 DB IF Rabbit Ig pSer1798 Log in to see Polyclonal
0.63784635 ABIN2497962 DB Rabbit Ig Fraction pSer1388 Log in to see Polyclonal
0.63784635 ABIN2497961 DB Rabbit Ig Fraction pSer1096 Log in to see Polyclonal
0.63784635 ABIN2497972 DB ELISA Rabbit Ig Fraction Log in to see Polyclonal
0.63784635 ABIN2497974 DB ELISA Rabbit Ig Fraction Log in to see Polyclonal
0.63784635 ABIN2497973 DB ELISA Rabbit Ig Fraction Log in to see Polyclonal
0.63784635 ABIN2497971 DB ELISA Rabbit Ig Fraction Log in to see Polyclonal
0.0008934913 ABIN358410 DB EIA Rabbit Ig pSer1798 Log in to see Polyclonal 5
0.0008934913 ABIN358369 DB EIA Rabbit Ig pSer664 Log in to see Polyclonal 5
0.0008934913 ABIN1952965 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Ser664 Log in to see Polyclonal
0.0008934913 ABIN1953037 DB ELISA WB Alkaline Phosphatase (AP) Rabbit IgG Ser939 Log in to see Polyclonal
0.0008934913 ABIN1952757 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Ser1388, pSer1388 Log in to see Polyclonal
0.0008934913 ABIN1952762 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Ser1420 Log in to see Polyclonal
0.0008934913 ABIN1952781 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Ser1798 Log in to see Polyclonal
0.0008934913 ABIN1953629 DB ELISA APC Rabbit IgG Ser1388, pSer1388 Log in to see Polyclonal

Top referenced anti-TSC2 antibody for Dot Blot

Similar anti-TSC2 Antibodies

Application / Reactivity Human
Dot Blot (DB) 120 Antibodies
ELISA 255 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 7 Antibodies
Flow Cytometry (FACS) 2 Antibodies
Immunochromatography (IC) 4 Antibodies
Immunocytochemistry (ICC) 26 Antibodies
Immunofluorescence (IF) 61 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 101 Antibodies
Immunohistochemistry (IHC) 153 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 80 Antibodies
Immunoprecipitation (IP) 7 Antibodies
Western Blotting (WB) 206 Antibodies

General

Antigen Tuberous Sclerosis 2 (TSC2) Antibodies
Epitope pSer1387
(41), (40), (34), (28), (27), (27), (24), (23), (22), (22), (20), (20), (20), (20), (20), (20), (20), (20), (20), (19), (17), (17), (16), (15), (15), (15), (13), (13), (13), (13), (11), (8), (8), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(523), (378), (209), (6)
Host Rabbit
(697), (24)
Clonality (Clone)
Polyclonal   ( )
Conjugate This TSC2 antibody is un-conjugated
(51), (51), (51), (43), (42), (42), (10), (10), (9), (9), (9), (9), (9), (9), (9), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Dot Blot (DB), Immunofluorescence (IF)
(387), (290), (219), (148), (101), (75), (62), (24), (7), (7), (4), (2), (1)
Pubmed 6 references available
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Product Details anti-TSC2 Antibody

Target Details TSC2 Application Details Handling References for anti-TSC2 Antibody (ABIN1881949) Images
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1387 of human TSC2.
Clone RB11388

Target Details TSC2

Product Details anti-TSC2 Antibody Application Details Handling References for anti-TSC2 Antibody (ABIN1881949) Images back to top
Antigen
Alternative Name TSC2 (TSC2 Antibody Abstract)
Background Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.

Synonyms: TSC2, TSC4, Tuberin, Tuberous sclerosis 2 protein
NCBI Accession NP_000539, NP_001070651, NP_001107854
UniProt P49815
Pathways RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-TSC2 Antibody Target Details TSC2 Handling References for anti-TSC2 Antibody (ABIN1881949) Images back to top
Application Notes DB: 1:500,IF: 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-TSC2 Antibody Target Details TSC2 Application Details References for anti-TSC2 Antibody (ABIN1881949) Images back to top
Format Liquid
Concentration 0.48 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-TSC2 Antibody (ABIN1881949)

Product Details anti-TSC2 Antibody Target Details TSC2 Application Details Handling Images back to top
Product cited in:

Huang, Ratovitski: "Phospho-?Np63?/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells." in: Aging, Vol. 2, Issue 12, pp. 959-68, 2011

Li, Inoki, Guan: "Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity." in: Molecular and cellular biology, Vol. 24, Issue 18, pp. 7965-75, 2004

Karbowniczek, Cash, Cheung, Robertson, Astrinidis, Henske: "Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent." in: The Journal of biological chemistry, Vol. 279, Issue 29, pp. 29930-7, 2004

Corradetti, Inoki, Bardeesy, DePinho, Guan: "Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome." in: Genes & development, Vol. 18, Issue 13, pp. 1533-8, 2004

Birchenall-Roberts, Fu, Bang, Dambach, Resau, Sadowski, Bertolette, Lee, Kim, Ruscetti: "Tuberous sclerosis complex 2 gene product interacts with human SMAD proteins. A molecular link of two tumor suppressor pathways." in: The Journal of biological chemistry, Vol. 279, Issue 24, pp. 25605-13, 2004

Lewis, Thomas, Murphy, Sampson: "Genotype and psychological phenotype in tuberous sclerosis." in: Journal of medical genetics, Vol. 41, Issue 3, pp. 203-7, 2004

Images

Product Details anti-TSC2 Antibody Target Details TSC2 Application Details Handling References for anti-TSC2 Antibody (ABIN1881949) back to top
Supplier Images
Dot Blot (DB) image for anti-TSC2 antibody (Tuberous Sclerosis 2) (pSer1387) (ABIN1881949) Dot blot analysis of Phospho-TSC2-S1387 polyclonal antibody (ABIN1881949) on nitrocel...
Immunofluorescence (IF) image for anti-TSC2 antibody (Tuberous Sclerosis 2) (pSer1387) (ABIN1881949) Dot blot analysis of Phospho-TSC2-S1387 polyclonal antibody (ABIN1881949) on nitrocel...