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anti-Mouse (Murine) TSC2 antibody for Immunocytochemistry

Recommended TSC2 Antibody (supplied by: Log in to see )

Antigen
Tuberous Sclerosis 2 (TSC2) Antibodies
  • fc16b02
  • LAM
  • Nafld
  • Rc
  • Tcs2
  • TSC2
  • TSC4
  • tuberin
  • wu:fc16b02
Epitope
N-Term
41
40
34
27
27
27
24
23
22
22
20
20
20
20
20
20
20
20
20
19
18
17
16
15
15
15
13
13
13
13
11
8
8
6
6
6
6
6
6
6
6
6
6
5
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
523
377
209
6
Host
Rabbit
697
24
Clonality
Polyclonal
Conjugate
This TSC2 antibody is un-conjugated
51
51
51
43
42
42
10
10
9
9
9
9
9
9
9
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
386
291
218
148
101
75
63
23
7
7
4
2
1
Supplier
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Available images

Catalog No. ABIN2500751
$ 535.71
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0009965416 ABIN1740412 ICC IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
0.0009965416 ABIN408095 ICC IF IHC (p) IHC WB Rabbit IgG Phe933 Log in to see Polyclonal
0.0009965416 ABIN1031646 ICC ELISA WB Rabbit N-Term Log in to see Polyclonal
0.0009965416 ABIN1888234 ICC ELISA WB Rabbit N-Term Log in to see Polyclonal
0.0009965416 ABIN1583813 ICC ELISA WB Rabbit Log in to see Polyclonal
0.0009965416 ABIN4363061 ELISA ICC IF IHC IHC (p) WB Rabbit N-Term Log in to see Polyclonal
0.0009965416 ABIN4363062 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0009965416 ABIN3068124 ICC IF IHC WB Rabbit C-Term, pThr1462 Log in to see Polyclonal

Similar anti-TSC2 Antibodies

Application / Reactivity Mouse (Murine) Human
Dot Blot (DB) 152 Antibodies 120 Antibodies
ELISA 167 Antibodies 255 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 7 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 9 Antibodies
Immunofluorescence (IF) 19 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 101 Antibodies
Immunohistochemistry (IHC) 49 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 48 Antibodies
Western Blotting (WB) 101 Antibodies
ELISA (Capture) 1 Antibodies
Flow Cytometry (FACS) 2 Antibodies

General

Antigen Tuberous Sclerosis 2 (TSC2) Antibodies
Epitope N-Term
(41), (40), (34), (27), (27), (27), (24), (23), (22), (22), (20), (20), (20), (20), (20), (20), (20), (20), (20), (19), (18), (17), (16), (15), (15), (15), (13), (13), (13), (13), (11), (8), (8), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(523), (377), (209), (6)
Host Rabbit
(697), (24)
Clonality
Polyclonal
Conjugate This TSC2 antibody is un-conjugated
(51), (51), (51), (43), (42), (42), (10), (10), (9), (9), (9), (9), (9), (9), (9), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
(386), (291), (218), (148), (101), (75), (63), (23), (7), (7), (4), (2), (1)
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Product Details anti-TSC2 Antibody

Target Details TSC2 Application Details Handling Images
Predicted Reactivity Human Mouse
Characteristics Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. TOR activity is stimulated by Rheb, a member of the Ras superfamily of G-proteins, when the GTP/GDP ratio bound to Rheb is high. Immunoprecipitated TSC1/TSC2 has been shown to stimulate Rheb GTPase activity in vitro, suggesting that the TSC1/TSC2 complex decreases the ability of Rheb to stimulate TOR activity. This is supported by experiments showing that overexpression of TSC1 and TSC2 results in a significant decrease in the GTP/GDP ratio bound to Rheb and the inhibition of cell growth. At least three isoforms of TSC2 exist.
Purification Affinity chromatography purified via peptide column
Immunogen The immunogen for anti-TSC2 antibody: tSC2 (NT) was raised against a 14 amino acid peptide from near the amino terminus of human TSC2.

Target Details TSC2

Product Details anti-TSC2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TSC2 (TSC2 Antibody Abstract)
Gene ID 7249
NCBI Accession NP_000539
Pathways RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-TSC2 Antibody Target Details TSC2 Handling Images back to top
Application Notes TSC2 antibody can be used for the detection of TSC2 by Western blot at 1 μg/mL. (Optimal dilution should be determined by user)
Restrictions For Research Use only

Handling

Product Details anti-TSC2 Antibody Target Details TSC2 Application Details Images back to top
Handling Advice As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
Storage 4 °C
Storage Comment TSC2 antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Expiry Date 12 months

Images

Product Details anti-TSC2 Antibody Target Details TSC2 Application Details Handling back to top
Supplier Images
Immunofluorescence (IF) image for anti-TSC2 antibody (Tuberous Sclerosis 2) (N-Term) (ABIN2500751) anti-Tuberous Sclerosis 2 (TSC2) (N-Term) antibody
Western Blotting (WB) image for anti-TSC2 antibody (Tuberous Sclerosis 2) (N-Term) (ABIN2500751) anti-Tuberous Sclerosis 2 (TSC2) (N-Term) antibody (Image 2)
Immunocytochemistry (ICC) image for anti-TSC2 antibody (Tuberous Sclerosis 2) (N-Term) (ABIN2500751) anti-Tuberous Sclerosis 2 (TSC2) (N-Term) antibody (Image 3)