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Metallocarboxypeptidase that mediates deglutamylation of target proteins. Additionally we are shipping AGBL4 Proteins (2) and many more products for this protein.
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study shows that Mad2 (show MXI1 Antibodies) is a novel substrate for CCP6 in megakaryocytes; Mad2 (show MXI1 Antibodies) polyglutamylation plays a crucial role in the regulation of megakaryopoiesis
ABGL4, LRP8 (show LRP8 Antibodies) and PCSK9 (show PCSK9 Antibodies) polymorphisms and gene interactions increase cardiometabolic risk.
AGBL4 promoter hypermethylation is associated with Colorectal Cancer.
Nna1 (show AGTPBP1 Antibodies) and CCP4 (show AGBL1 Antibodies) remove the C-terminal glutamate (show GRIN1 Antibodies) from substrates with two or more glutamates, whereas CCP6 requires four or more glutamates. CCP4 (show AGBL1 Antibodies) behaves as a promiscuous glutamase with little preference for chain length or neighboring amino acid composition
Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.
ATP/GTP binding protein-like 4
, ATP/GTP-binding protein-like 4
, cytosolic carboxypeptidase 6
, cytosolic carboxypeptidase 6-like