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The protein encoded by CHI3L2 is similar to bacterial chitinases but lacks chitinase activity. Additionally we are shipping Chitinase 3-Like 2 Antibodies (74) and Chitinase 3-Like 2 Kits (8) and many more products for this protein.
Showing 9 out of 11 products:
This study suggests that CHI3L1 (show CHI3L1 Proteins) and CHI3L2 are associated with the progression of neurodegeneration in motor cortex and spinal cord of Amyotrophic Lateral Sclerosis patients.
This study shown that CHI3L2 is regulated differently in healthy and late onset Alzheimer"s disease brain depending on the sex.
This review comprehensively analyzes recent data about expression pattern, and involvement of human YKL-40 (show CHI3L1 Proteins), YKL-39 and SI-CLP (show CHID1 Proteins) in cancer. [review]
cerebrospinal fluid CHI3L1 (show CHI3L1 Proteins) and CHI3L2 and serum CHI3L1 (show CHI3L1 Proteins) might help to define multiple sclerosis disease stage
Structural analysis demonstrates that YKL-39 interacts with chitooligosaccharides through hydrogen bonds and hydrophobic interactions. Thermodynamic analysis indicates that binding of chitooligosaccharide to YKL-39 is mainly driven by enthalpy.
YKL-39 possesses a chitinase-like fold, but lacks key active-site residues required for catalysis.
ERK1/2 phosphorylation by CHI3L2 inhibits cell mitogenesis and proliferation.
human chitinase 3-like 2 gene (YKL-39) but not chitinase 3-like 1 gene (YKL-40 (show CHI3L1 Proteins)) is upregulated in osteoarthritic cartilage
The protein encoded by this gene is similar to bacterial chitinases but lacks chitinase activity. The encoded protein is secreted and is involved in cartilage biogenesis. Several transcript variants encoding different isoforms have been found for this gene.
chitinase-3-like protein 2
, chondrocyte protein 39