Chromobox Homolog 5 Proteins (CBX5)

Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Additionally we are shipping CBX5 Antibodies (269) and CBX5 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CBX5 23468 P45973
Rat CBX5 CBX5 300266  
CBX5 12419 Q61686
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online

Top CBX5 Proteins at

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 10 to 12 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days

CBX5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Chromobox Homolog 5 (CBX5) Interaction Partners

Human Chromobox Homolog 5 (CBX5) interaction partners

  1. Data suggest that SUMOylated heterochromatin protein 1-alpha (HP1alpha)alpha is a critical epigenetic-regulator of DNA-repair in breast cancer (BCa (show BLNK Proteins)) that could define chemotherapy responsiveness.

  2. findings suggest that heterochromatin-mediated gene silencing may occur in part through sequestration of compacted chromatin in phase-separated HP1 (show DEFA1 Proteins) droplets, which are dissolved or formed by specific ligands on the basis of nuclear context

  3. Data show that SALL4 (show SALL4 Proteins) promotes the expression of Glut1 (show SLC2A1 Proteins) and open chromatin through a HP1alpha-dependent mechanism.

  4. Identify a nucleosome interaction module within KDM2A (show KDM2A Proteins) consisting of a CXXC type zinc finger, a PHD (show PDC Proteins) domain and a newly identified Heterochromatin Protein 1 (HP1 (show DEFA1 Proteins)) interaction motif that mediates direct binding between KDM2A (show KDM2A Proteins) and HP1 (show DEFA1 Proteins). This nucleosome interaction module enables KDM2A (show KDM2A Proteins) to decode nucleosomal H3K9me3 modification in addition to CpG methylation signals.

  5. These data suggests that up-regulated HP1A (show TFF1 Proteins) and H3K9me3 in glioma cells are functionally associated with glioma pathogenesis and progression.

  6. Loss of HP1alpha and gamma isoforms inhibits the upregulation of Suv39h1 (show SUV39H1 Proteins) and H3K9me3 that is observed under stress conditions.

  7. we showed the essential role of HP1 (show DEFA1 Proteins) in regulating HR through BRCA1/BARD1 (show BARD1 Proteins)-mediated accumulation of FANCJ and CtIP (show RBBP8 Proteins) at DSB sites. This mechanism may affect tumorigenesis and chemosensitivity and is thus of high clinical significance.

  8. We demonstrate that an hnRNPA1 (show HNRNPA1 Proteins) and CBX5 bi-directional core promoter fragment does not comprise intrinsic capacity for specific CBX5 down-regulation in metastatic cells

  9. HP1alpha plays an important role in the differentiation and angiogenic function of Endothelial Progenitor Cells.

  10. Jra recruits the HP1a (show TFF1 Proteins)/KDM4A (show KDM4A Proteins) complex to its gene body region upon osmotic stress to reduce H3K36 methylation levels and disrupt H3K36 methylation-dependent histone deacetylation

Mouse (Murine) Chromobox Homolog 5 (CBX5) interaction partners

  1. HP1-alpha oligomerization is critical to the maintenance of heterochromatin and the tunable dynamics of this HP1 isoform.

  2. demonstrate an actin-driven differential modulation of core histone H2B and heterochromatin HP1alpha protein dynamics with chromatin

  3. the molecular behavior of HP1alpha throughout the cell cycle

  4. There is a functional link between prelamin A, HP1alpha, chromatin remodeling, DNA repair, and early senescence in Zmpste24 (show Zmpste24 Proteins)-deficient mice, suggesting a potential therapeutic strategy for laminopathy-based premature aging via the intervention of HP1alpha.

  5. the TIF1beta (show TRIM28 Proteins)-HP1 system functions as a critical repressive machinery that targets genes not normally activated in the hematopoietic compartment, thereby maintaining the transcriptional signature specific to HSCs.

  6. HP1 mobility in apoptotic cells appeared to be unique.

  7. Elimination of HP1alpha by siRNA interfered with centromere relocation from heterochromatin surrounding NPBs to pro-chromocenters at the two-cell stage but did not affect preimplantation develoment to the blastocyst stage.

  8. Depletion of Senp7 (show SENP7 Proteins) delocalizes HP1 alpha from pericentric heterochromatin without affecting H3K9me3 levels.

  9. The interplay between MU2 (show AP2M1 Proteins) and HP1a is dynamic and may be different in euchromatin and heterochromatin during DNA break recognition and repair.

  10. KAP1 (show TRIM28 Proteins) and HP1 tether activation-induced cytidine deaminase (show AICDA Proteins) (AID) to H3K9me3 residues at the donor switch region, thus linking AID to epigenetic modifications during class switch recombination.

CBX5 Protein Profile

Protein Summary

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with Chromobox Homolog 5 Proteins (CBX5)

  • chromobox 5 (CBX5)
  • chromobox homolog 5 (HP1 alpha homolog, Drosophila) (cbx5)
  • chromobox 5 (Cbx5)
  • chromobox 5 S homeolog (cbx5.S)
  • chromobox 5 (cbx5)
  • 2610029O15Rik protein
  • C75991 protein
  • cbx5 protein
  • HP1 protein
  • Hp1a protein
  • Hp1alpha protein
  • id:ibd2026 protein
  • MGC64354 protein
  • wu:fc63e02 protein
  • wu:fe47g12 protein
  • wu:fi03h05 protein
  • zgc:158601 protein

Protein level used designations for Chromobox Homolog 5 Proteins (CBX5)

HP1 alpha homolog , HP1-ALPHA , HP1Hs alpha , antigen p25 , chromobox homolog 5 (HP1 alpha homolog, Drosophila) , chromobox protein homolog 5 , heterochromatin protein 1 homolog alpha , heterochromatin protein 1-alpha , fc63e02 , chromobox-like protein 5 , chromobox-like protein 5 (HP1 alpha homolog, Drosophila) , HP1 alpha , chromobox homolog 5 , heterochromatin protein 1 alpha , mHP1(alpha) , chromobox homolog 5 tv3

23468 Homo sapiens
563396 Danio rerio
538885 Bos taurus
477593 Canis lupus familiaris
467011 Pan troglodytes
300266 Rattus norvegicus
100307036 Ovis aries
380557 Xenopus laevis
394502 Xenopus (Silurana) tropicalis
12419 Mus musculus
100519426 Sus scrofa
Selected quality suppliers for CBX5 Proteins (CBX5)
Did you look for something else?