Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
CIITA encodes a protein with an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain. Additionally we are shipping Class II, Major Histocompatibility Complex, Transactivator Proteins (3) and many more products for this protein.
Showing 10 out of 49 products:
Pig (Porcine) Polyclonal CIITA Primary Antibody for WB - ABIN97339
Koues, Dudley, Mehta, Greer: The 19S proteasome positively regulates histone methylation at cytokine inducible genes. in Biochimica et biophysica acta 2009
This gene encodes a protein with an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain. The protein is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the 'master control factor' for the expression of these genes. The protein also binds GTP and uses GTP binding to facilitate its own transport into the nucleus. Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion. Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction.
class II, major histocompatibility complex, transactivator
, class II transactivator-like
, class II transactivator
, MHC class II transactivator-like
, MHC class II transactivator
, MHC class II transactivator type III
, NLR family, acid domain containing
, nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing
, MHC class II transactivator type IV