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The protein encoded by IBSP is a major structural protein of the bone matrix. Additionally we are shipping Integrin-Binding Sialoprotein Kits (16) and Integrin-Binding Sialoprotein Proteins (9) and many more products for this protein.
Showing 10 out of 91 products:
Human Polyclonal IBSP Primary Antibody for IF (p), IHC (p) - ABIN748838
Yang, Hai, Qin, Ti, Shangguan, Zhao, Wiggins, Liu, Feng, Chang, Wang, Liu: Cessation of epithelial Bmp signaling switches the differentiation of crown epithelia to the root lineage in a ?-catenin-dependent manner. in Molecular and cellular biology 2013
Show all 2 Pubmed References
These data indicate that secretome derived from salivary gland cancer cells can influence the expression of two potential biomarkers of oral cancer-namely, bone sialoprotein (show CRISP1 Antibodies) (BSP (show KLK6 Antibodies)) and dentin sialoprotein (DSP (show DSPP Antibodies))-in normal salivary gland cells.
In conclusion, serum levels of BSP, ALP, ICTP, and PSA increased in patients with bone metastases, and combined detection of all markers could improve the positive-predictive value.
Preameloblast-Derived Factors Mediate Osteoblast Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Runx2 (show RUNX2 Antibodies)-Osterix (show SP7 Antibodies)-BSP (show KLK6 Antibodies) Signaling.
Two significant SNPs within IBSP, rs1054627 and rs17013181, were associated with BMD (show BEST1 Antibodies) and postmenopausal osteoporosis by the two-stage strategy, and rs17013181 was also significantly associated with serum IBSP levels.
Our results suggest that SSEA (show MPST Antibodies)-4 is a specific cell surface antigen (show CD53 Antibodies) that can be used to identify dental pulp stem cells.
the strong correlation between bone sialoprotein (show CRISP1 Antibodies) and OPN (show SPP1 Antibodies) and papillary thyroid carcinoma suggests a role for BSP (show KLK6 Antibodies) and OPN (show SPP1 Antibodies) in calcification and tumor progression of papillary thyroid carcinoma
oxidized low-density lipoprotein-induced expression dependent on Runx2 (show RUNX2 Antibodies) expression
Bone sialoprotein (show CRISP1 Antibodies) could be a key mediator of the hypertrophic chondrocytes-induced angiogenesis of osteoarthritis.
Current evidence demonstrates that BSP (show KLK6 Antibodies) and OPN (show SPP1 Antibodies), play significant roles in bone metastasis of osteotropic malignancies derived from breast, prostate, lung, thyroid, and multiple myeloma. [review]
High expression of bone sialoprotein (show CRISP1 Antibodies) in breast neoplasms was associated with cytokeratin (show KRT4 Antibodies)-positive cells in bone marrow, but not with lymph node metastasis.
Data indicate that BSP (show KLK6 Antibodies) is present in the calcified fibrocartilage of murine entheses and suggest that BSP (show KLK6 Antibodies) plays a regulatory role in this structure, influencing the growth of the calcified fibrocartilage in addition to the weakening of the tendon mechanical properties.
Bone marrow ablation in BSP (show KLK6 Antibodies)-/- mice is followed by a faster vascular and hematopoietic recolonization, along with lower medullary bone formation. Thus, lack of BSP (show KLK6 Antibodies) affects the interplay between hematopoiesis, angiogenesis, and osteogenesis, maybe in part through higher expression of VEGF (show VEGFA Antibodies) and the angiogenic SIBLING, OPN (show SPP1 Antibodies).
a bone sialoprotein (show CRISP1 Antibodies)-null bone microenvironment affects the hematopoietic system both quantitatively and qualitatively
full expression of either OPN (show SPP1 Antibodies) or BSP (show KLK6 Antibodies) is necessary for the anabolic effect of PTH (show PTH Antibodies) at least in the ectopic calvaria injection model
BSP (show KLK6 Antibodies) plays a non-redundant role in acellular cementum formation, likely involved in initiating mineralization on the root surface. Through its importance to cementum integrity, BSP (show KLK6 Antibodies) is essential for periodontal function.
Lack of BSP (show KLK6 Antibodies) affects both osteoclast formation and activity.
bone sialoprotein (show CRISP1 Antibodies) has a role in neoplasm metastasis
BSP (show KLK6 Antibodies) gene transcription is autoregulated in part by a positive feedback on its own promoter.
Bsp (show KLK6 Antibodies) mRNA is expressed in developing testis cords and thus may contribute to testis differentiation
BSP (show KLK6 Antibodies) contributes to RANKL (show TNFSF11 Antibodies)-mediated bone resorption by inducing osteoclastogenesis and osteoclast survival and decreasing osteoclast apoptosis
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
, bone sialoprotein 2
, bone sialoprotein II
, cell-binding sialoprotein
, integrin binding sialoprotein
, integrin-binding sialoprotein
, integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II)
, Bone sialoprotein 2