anti-Major Histocompatibility Complex, Class II, DO beta (HLA-DOB) Antibodies

HLA-DOB belongs to the HLA class II beta chain paralogues. Additionally we are shipping HLA-DOB Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HLA-DOB 3112 P13765
HLA-DOB    
HLA-DOB    
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Top anti-HLA-DOB Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of HLA-DOB expression in HeLa (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: HLA DOB Antibody [NBP1-87469] - Immunohistochemical staining of human lymph node shows strong nuclear and cytoplasmic positivity in reaction center cells. Immunohistochemistry-Paraffin: HLA DOB Antibody  - Staining of human tonsil shows high expression. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB ABIN6275187 staining  293 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IP, WB HLA-DOB MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DOB expression in human placenta. Immunoprecipitation of HLA-DOB transfected lysate using anti-HLA-DOB MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with HLA-DOB purified MaxPab mouse polyclonal antibody (B01P) . 100 μL Log in to see 11 to 12 Days
$343.47
Details
Human Mouse Un-conjugated WB Western Blot analysis of HLA-DOB expression in transfected 293T cell line by HLA-DOB MaxPab polyclonal antibody.Lane 1: HLA-DOB transfected lysate(30.03 KDa).Lane 2: Non-transfected lysate. HLA-DOB MaxPab polyclonal antibody. Western Blot analysis of HLA-DOB expression in human liver. 50 μL Log in to see 11 to 12 Days
$354.20
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.01 KDa) . 50 μL Log in to see 11 to 12 Days
$231.53
Details
Human Rabbit Un-conjugated WB HLA-DOB MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DOB expression in human placenta. Western Blot analysis of HLA-DOB expression in transfected 293T cell line by HLA-DOB MaxPab polyclonal antibody.Lane 1: HLA-DOB transfected lysate(30.80 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 11 to 12 Days
$343.47
Details

More Antibodies against HLA-DOB Interaction Partners

Human Major Histocompatibility Complex, Class II, DO beta (HLA-DOB) interaction partners

  1. results indicate that HLA-DOB is co-inherited with DQA2-B2 genes and thus may contribute to HCV and HBV persistence

  2. TAP2 (show TAP2 Antibodies), HLA-DOA (show HLA-DOA Antibodies), HLA-DOB, and tapasin (show TAPBP Antibodies) loci are novel candidate regions for susceptibility to HCV infection and viral clearance in the Chinese population

  3. HLA-DOB mutations were analyzed for association with autoimmune diseases and B-cell leukemias.

  4. In transgenic mice expressing human HLA-DOA & HLA-DOB from a DC-specific promoter, as DO increased, A(b)-CLIP increased & class II-peptides decreased. DO impaired H-2M function, causing Ag-specific downmodulation of class II Ag processing/presentation.

  5. A new DOB allele, DOB*010103, was identified in the Korean population during sequence-based HLA-DOB typing.

HLA-DOB Antigen Profile

Protein Summary

HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.

Gene names and symbols associated with HLA-DOB

  • major histocompatibility complex, class II, DO beta (HLA-DOB) antibody
  • DOB antibody

Protein level used designations for HLA-DOB

HLA class II histocompatibility antigen, DO beta chain , MHC class II antigen DOB

GENE ID SPECIES
3112 Homo sapiens
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