anti-Meprin A, beta (MEP1B) Antibodies

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. Additionally we are shipping Meprin B Kits (15) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MEP1B 17288 Q61847
MEP1B 25727 P28826
MEP1B 4225 Q16820
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Top anti-Meprin B Antibodies at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Rat Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Rat Kidney Tissue; Lane2: Rat Intestine Tissue. 100 μg Log in to see 13 to 16 Days
$342.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry: Meprin beta Subunit/MEP1B Antibody [NBP2-37865] - Staining of human small intestine shows strong membranous positivity in glandular cells. Western Blot: Meprin beta Subunit/MEP1B Antibody [NBP2-37865] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: RT-4.Lane 3: U-251 MG.Lane 4: Human Plasma.Lane 5: Liver.Lane 6: Tonsil 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Mouse Rabbit Un-conjugated WB Western blot analysis of extracts of mouse kidney cells, using MEP1B antibody. 100 μL Log in to see 16 Days
$334.77
Details
Human Chicken Un-conjugated WB Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. (anti-MEP1B) 0.05 mg Log in to see 7 to 9 Days
$585.06
Details
Rat Rabbit Un-conjugated IF/ICC, IHC, IP, WB Western blot analysis of (1) Rat Kidney Tissue and (2) Rat Intestine Tissue. Western blot analysis of recombinant Rat MEP1b. 100 μg Log in to see 11 to 18 Days
$440.62
Details
Human Chicken Un-conjugated WB 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 16 Days
$221.38
Details
Rat Rabbit Un-conjugated WB   100 μL Log in to see 7 to 9 Days
$390.50
Details
Human Chicken Un-conjugated ELISA, WB   50 μg Log in to see 11 to 16 Days
$579.86
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μL Log in to see 11 to 18 Days
$440.62
Details

More Antibodies against Meprin B Interaction Partners

Zebrafish Meprin A, beta (MEP1B) interaction partners

Mouse (Murine) Meprin A, beta (MEP1B) interaction partners

  1. This secreted cysteine protease (show CTSW Antibodies) potently converts membrane-bound meprin beta into its active form, impairing meprin beta shedding and its function as a mucus-detaching protease

  2. no significant dentin malformation was observed in Mep1b (-/-) or Mep1a (show MEP1A Antibodies) (-/-) deficient mice.

  3. meprin alpha (show MEP1A Antibodies) and meprin beta join the modulators of Reelin (show RELN Antibodies) signalling as they cleave Reelin (show RELN Antibodies) at a specific site and are upregulated under specific pathological conditions.

  4. These studies provide strong evidence for a pathophysiological link between meprin beta and urinary excretion of cleaved nidogen-1 (show NID1 Antibodies) during cisplatin-induced acute kidney injury.

  5. While meprin A only cleaved protein kinase A (PKA) catalytic subunit beta1, meprin B cleaved all three PKA catalytic isoforms.

  6. Meprin beta is an endogenous zinc-dependent metalloprotease (show ADAMTS7 Antibodies) now shown to cleave the N-terminal region of the MUC2 (show MUC2 Antibodies) mucin (show SLC13A2 Antibodies) at two specific sites.

  7. Suggest role for in meprin-beta-Fra2 (show FOSL2 Antibodies) axis in mediating vascular remodelling in pulmonary hypertension.

  8. meprin alpha (show MEP1A Antibodies) and meprin beta are unique in their ability to process and release both C- and N-propeptides from type I procollagen (show COL1A2 Antibodies) in vitro and in vivo

  9. of the 151 new extracellular substrates identified, it was notable that ADAM10 (show ADAM10 Antibodies) the constitutive alpha-secretase-is activated by meprin beta through cleavage of the propeptide

  10. the binding of S-MBP to meprins triggers the complement activation through the lectin pathway and may cause the acute renal failure due to ischemia/reperfusion injury on kidney transplantation and hemorrhagic shock

Human Meprin A, beta (MEP1B) interaction partners

  1. This secreted cysteine protease (show CTSB Antibodies) potently converts membrane-bound meprin beta into its active form, impairing meprin beta shedding and its function as a mucus-detaching protease

  2. For meprin beta a reduction and for BMP-1 (show BMP1 Antibodies) an increase in activity was reported under increasing calcium concentrations.

  3. In this review we report on recent findings that summarize the complex molecular regulation of meprins, particular folding, activation and shedding. Dysregulation of meprin alpha (show MEP1A Antibodies) and meprin beta is often associated with pathological conditions such as neurodegeneration, inflammatory bowel disease and fibrosis

  4. TSPAN8 (show TSPAN8 Antibodies) might be important for the orchestration of meprin beta at the cell surface with impact on certain proteolytic processes

  5. n conclusion, we show that the concept of cleavable linkers specific for meprin beta is feasible, as the peptides are rapidly cleaved by the enzyme while retaining their biological properties

  6. Meprin Beta was found to be activated at the cell surface by matriptase-2 (show TMPRSS6 Antibodies).

  7. promotes inflammation in macrophages via ADAM-10 (show ADAM10 Antibodies) dependent pathway

  8. Overexpression of MEP1B is associated with pancreatic neuroendocrine tumors.

  9. Suggest role for in meprin-beta-Fra2 (show FOSL2 Antibodies) axis in mediating vascular remodelling in pulmonary hypertension.

  10. Meprin metalloproteases A and B inactivate interleukin 6 (show IL6 Antibodies)

Meprin B (MEP1B) Antigen Profile

Protein Summary

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.

Gene names and symbols associated with anti-Meprin A, beta (MEP1B) Antibodies

  • meprin A subunit beta (MEP1B) antibody
  • meprin A subunit beta (LOC100031050) antibody
  • meprin A subunit beta (mep1b) antibody
  • meprin A, beta (mep1b) antibody
  • meprin A subunit beta (LOC100545010) antibody
  • meprin 1 beta (Mep1b) antibody
  • meprin A subunit beta (Mep1b) antibody
  • Mep-1b antibody
  • MEP1B antibody
  • si:ch211-191a24.6 antibody
  • zgc:153272 antibody

Protein level used designations for anti-Meprin A, beta (MEP1B) Antibodies

meprin A, beta , N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase beta , meprin A subunit beta , meprin A subunit beta-like , endopeptidase-2 , meprin B , meprin beta , meprin A beta , N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta , N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase beta subunit , PABA peptide hydrolase , PPH beta

GENE ID SPECIES
421097 Gallus gallus
468515 Pan troglodytes
490497 Canis lupus familiaris
540701 Bos taurus
707036 Macaca mulatta
100031050 Monodelphis domestica
100124942 Xenopus (Silurana) tropicalis
100151009 Danio rerio
100406280 Callithrix jacchus
100461703 Pongo abelii
100474827 Ailuropoda melanoleuca
100516141 Sus scrofa
100545010 Meleagris gallopavo
100563868 Anolis carolinensis
100587715 Nomascus leucogenys
17288 Mus musculus
25727 Rattus norvegicus
4225 Homo sapiens
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