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The protein encoded by NLRC3 is a cytosolic regulator of innate immunity. Additionally we are shipping and many more products for this protein.
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NLRC3 promoted K48-linked polyubiquitination and degradation of interleukin-1 receptor-associated kinase 1 (IRAK1).
The NLRC3 interferes with the assembly and activity of the NALP3 inflammasome complex by competing with ASC for pro-caspase-1 binding.
The extent of NLRC3 and AIM2 gene reduction was correlated with cancer progression.
NLRX1, NLRP12 and NLRC3 negatively modulate the host immune response following virus exposure. (Review)
overexpression of NLRC3 with NLRP3/cryopyrin inflammasome components suppresses pro-caspase-1 cleavage and IL-1beta processing.
Post-transcriptional inhibition of luciferase reporter assays by the Nod-like receptor proteins NLRX1 and NLRC3.
NLRC3 inhibited Toll-like receptor (TLR)-dependent activation of the transcription factor NF-kappaB by interacting with the TLR signaling adaptor TRAF6
This report describes the first cloning and characterization of a novel CATERPILLER gene, CLR16.2 that is located on human chromosome 16. The protein encoded by this gene has a typical NBD-LRR configuration.
NLRC3 serves as a potential target for therapeutic intervention against tuberculosis.
NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING.
The protein encoded by this gene is a cytosolic regulator of innate immunity. The encoded protein contains several leucine-rich repeat domains and may be involved in regulating T-cell activation. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene.
NLR family, CARD domain containing 3
, NOD3 protein
, nucleotide-binding oligomerization domain containing 3
, CARD15-like protein
, NOD-like receptor C3
, caterpiller protein 16.2
, nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 3
, protein NLRC3
, Caterpiller 16.2
, caterpillar 16.2
, NLR family, CARD domain containing 3, pseudogene 1