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Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. Additionally we are shipping Nucleoporin 43kDa Proteins (5) and many more products for this protein.
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Cow (Bovine) Polyclonal NUP43 Primary Antibody for WB - ABIN2786439
Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: The LIFEdb database in 2006. in Nucleic acids research 2005
High NUP43 expression was an independent prognostic factor of poor overall survival in luminal A subtype and in HER2+ subtype breast cancer.
Data present the crystal structure of full length Nup43 and show that it adopts a canonical WD40 fold similar to other members of the family and interacts with Nup85-Seh1L complex to form a ternary complex.
Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004
, nucleoporin Nup43-like
, nucleoporin Nup43
, nup107-160 subcomplex subunit Nup43