anti-RAP2A, Member of RAS Oncogene Family (RAP2A) Antibodies

human homolog is a GTPase and member of the RAS oncogene family [RGD, Feb 2006].. Additionally we are shipping RAP2A Proteins (7) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RAP2A 114560  
RAP2A 5911 P10114
RAP2A 76108 Q80ZJ1
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Top anti-RAP2A Antibodies at antibodies-online.com

Showing 10 out of 22 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated IHC, IHC (p), WB Anti-RAP2 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1103905 dilution 10 ug/ml. Anti-RAP2 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using RAP2A antibody (ABIN1874550) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s. 100 μL 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using RAP2A antibody (ABIN5971429) at 1/1000 dilution. 100 μL 11 to 16 Days
$426.40
Details
Bat Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$551.83
Details
Bat Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$551.83
Details
Dog Rabbit Un-conjugated IHC, WB   100 μg 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated WB 100 μg 2 to 3 Days
$258.46
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of RAP2A expression in transfected 293T cell line by RAP2A polyclonal antibody (A01).Lane1:RAP2A transfected lysate(20.6 KDa).Lane2:Non-transfected lysate. Western Blot detection against Immunogen (46.24 KDa) . 50 μL 11 to 12 Days
$305.71
Details

Top referenced anti-RAP2A Antibodies

  1. Chicken Polyclonal RAP2A Primary Antibody for IHC (p), WB - ABIN4349356 : Lee, He, Chen, Lee, Chang, Hsing, Li: The prognostic impact of RAP2A expression in patients with early and locoregionally advanced nasopharyngeal carcinoma in an endemic area. in American journal of translational research 2015 (PubMed)

More Antibodies against RAP2A Interaction Partners

Human RAP2A, Member of RAS Oncogene Family (RAP2A) interaction partners

  1. Disrupting CD147-RAP2 interaction abrogates erythrocyte invasion by Plasmodium falciparum.

  2. The phosphorylation also produces an increase in GAP activity toward Rap2 , an effect not produced by either kinase alone.

  3. RAP2 mediates mechanoresponses of the Hippo pathway; RAP2 is a molecular switch in mechanotransduction, thereby defining a mechanosignalling pathway from extracellular matrix stiffness to the nucleus

  4. These findings indicate that Rap2a promotes renal cell carcinoma metastasis and may serve as a candidate renal cell carcinoma prognostic marker and a potential therapeutic target.

  5. The small GTPase Ras-related protein 2 (Rap2) was found to bind ArrB1 under resting conditions but dissociated upon formyl-Met-Leu-Phe stimulation.

  6. Nedd4-1 inhibited Rap2a activity, and promoted the migration and invasion of glioma cells.

  7. present review mainly focused on recent studies on the functional and physical interactions between Rap2 and its effectors. We also speculated on the relevance of these pathways to tumorigenesis

  8. Single nucleotide polymorphism in RAP2A gene is associated with Peripheral Arterial Disease.

  9. the role of Rap2a in carcinogenesis

  10. The ectopic expression of Rap2a enhances the migration and invasive ability of cancer cells and increases activities of matrix metalloproteinase MMP2 and MMP9.

  11. Phosphorylation of synaptic GTPase-activating protein (synGAP) by Ca2+/calmodulin-dependent protein kinase II (CaMKII) and cyclin-dependent kinase 5 (CDK5) alters the ratio of its GAP activity toward Ras and Rap GTPases.

  12. downregulation of Rap2a promoted glioma migration and invasion, and raised the phosphorylation level of AKT

  13. endothelial barrier resistance is determined by the combined antagonistic actions of Rap1 and Rap2

  14. Rap2A and TNIK control brush border formation by apical recruitment of MST4 and the subsequent phosphorylation of Ezrin

  15. Rap2 enhanced MAP4K4-induced activation of JNK

  16. TNIK is a specific effector of Rap2 to regulate actin cytoskeleton

  17. RGS14 activity towards heterotrimeric G-proteins, as either a GAP or a guanine nucleotide dissociation inhibitor, was unaffected by Rap binding.

  18. RT-PCR analysis of mRNA extracted from highly purified reticulocytes confirmed the expression of Rap2b, but not Rap2a, Rap2c, Rap1a or Rap1b.

  19. A study that demonstrated the engagement of beta2 integrins on human neutrophils increased the levels of GTP-bound Rap1 and Rap2 is presented.

  20. interaction surfaces in RAPL-Rap1 and RAPL-Rap2 complexes are different and that a single residue in the switch I region of Rap proteins (residue 39) contributes considerably to the different kinetics of these protein-protein interactions.

Mouse (Murine) RAP2A, Member of RAS Oncogene Family (RAP2A) interaction partners

  1. These results implicate Rap2a in TLR-mediated responses by contributing to balanced NF-kappaB activity status in macrophages.

  2. The small GTP-binding protein Rap2a is a common target of both miR-9 and miR-124. miR-9 and miR-124 together, but neither miRNA alone, strongly suppressed Rap2a, thereby promoting neuronal differentiation of neural stem cells and dendritic branching of differentiated neurons. Rap2a also diminished the dendritic complexity of mature neurons by decreasing the levels of pAKT and pGSK3beta.

  3. BCR-induced phosphorylation of Akt on critical activating sites was increased 2- to 3-fold when Rap1 and Rap2 activation was blocked

  4. Rap2 has a role in regulation of integrin-mediated adhesion, cell spreading, actin polymerization, and Pyk2 tyrosine phosphorylation in B lymphocytes

RAP2A Antigen Profile

Protein Summary

human homolog is a GTPase and member of the RAS oncogene family

Gene names and symbols associated with RAP2A

  • RAP2A, member of RAS oncogene family (RAP2A) antibody
  • RAP2A, member of RAS oncogene family (Rap2a) antibody
  • RAP2A, member of RAS oncogene family (rap2a) antibody
  • Rap2A GTPase (rap2a) antibody
  • RAP2B, member of RAS oncogene family (RAP2B) antibody
  • RAS related protein 2a (Rap2a) antibody
  • 5830461H18Rik antibody
  • K-REV antibody
  • KREV antibody
  • RAP2 antibody
  • RAP2A antibody
  • RbBP-30 antibody

Protein level used designations for RAP2A

ras-related protein Rap-2a , RAS related protein 2a inverted question mark , rap2A-like protein , RAP2A, member of RAS oncogene family , Rap2A GTPase , RAP2, member of RAS oncogene family (K-rev) , RAP2B member of RAS oncogene family , Ras-related protein Rap-2a

GENE ID SPECIES
522707 Bos taurus
114560 Rattus norvegicus
619593 Xenopus (Silurana) tropicalis
100302081 Ovis aries
414291 Xenopus laevis
5911 Homo sapiens
100144507 Sus scrofa
100172918 Pongo abelii
76108 Mus musculus
769797 Gallus gallus
452629 Pan troglodytes
476968 Canis lupus familiaris
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