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The protein encoded by RIPK4 is a serine/threonine protein kinase that interacts with protein kinase C-delta. Additionally we are shipping RIPK4 Proteins (6) and many more products for this protein.
Showing 10 out of 62 products:
Human Monoclonal RIPK4 Primary Antibody for ELISA, WB - ABIN565712
Adams, Munz: RIP4 is a target of multiple signal transduction pathways in keratinocytes: implications for epidermal differentiation and cutaneous wound repair. in Experimental cell research 2009
Overexpression of EZH2 (show EZH2 Antibodies) was found in 30 patients (76.9%) and was associated with FIGO stage, histological type, and lymph node metastasis (p < 0.05). In conclusion, our data suggest that RIPK4/EZH2 (show EZH2 Antibodies) markers might be used as potential predictors of prognosis in cervical cancer.
These findings position RIPK4 upstream of a hierarchal IRF6 (show IRF6 Antibodies)-GRHL3 (show GRHL3 Antibodies)-ELF3 (show ELF3 Antibodies) transcription factor pathway in keratinocytes.
CHAND and Bartsocas-Papas (show PSTPIP1 Antibodies) syndrome might be allelic disorders or RIPK4 mutations could confer varying degrees of phenotypic severity, depending on their localization within or outside functionally important domains.
we identified an epithelial ovarian cancer susceptibility loci at 10p11.21 (rs1192691 near ANKRD30A, P(meta) = 2.62 x 10(-8))
The p.Ser376X mutation in RIPK4 impaired its induction of IRF6 (show IRF6 Antibodies) transactivator function.
Suppression of PKK expression by RNA interference inhibits phosphorylation of IKKalpha (show CHUK Antibodies) and IKKbeta (show IKBKB Antibodies) as well as activation of NF-kappaB (show NFKB1 Antibodies) in human cancer cell lines; thus, PKK regulates NF-kappaB (show NFKB1 Antibodies) activation by modulating activation of IKKalpha (show CHUK Antibodies) and IKKbeta (show IKBKB Antibodies).
The protein kinase C-associated kinase (PKK), which is also known as the receptor-interacting protein (show RIPK1 Antibodies) kinase (show CDK7 Antibodies) 4, is a suppressor of tumor growth in squamous cell carcinoma of the skin.
Data indicate protein-serine-threonine kinases RIPK4 overexpression in transformed fetal hepatocytes.
Authors found a correlation between RIPK4 expression and TSCC degree of differentiation, age, and gender.
Ser (show SIGLEC1 Antibodies)-413 and Ser (show SIGLEC1 Antibodies)-424 in IRF6 (show IRF6 Antibodies) are important for its activation by RIPK4
This approach identified a key signaling event, phosphorylation of a desmosome component, PKP1 (plakophilin-1 (show PKP1 Antibodies)) by RIPK4 (receptor-interacting serine-threonine kinase 4) during epidermal differentiation.
RIP4 functions in the epidermis through PKC-specific signaling pathways to regulate differentiation and inflammation
a member of the RICK/RIP (show HRB Antibodies) family of kinases, which is involved in a PKC (show PKC Antibodies)-activated NF-kappa B (show NFKB1 Antibodies) signaling pathway that is independent of Bcl10 (show BCL10 Antibodies) and IKK gamma (show IKBKG Antibodies)
Data show that RIP4 is a critical component of a novel pathway that controls keratinocyte differentiation.
PKK may be required early in B cell development and for B cell receptor-mediated B cell proliferation.
PKK is not required for the production of B cells in the bone marrow or for the development and maintenance of all mature B lymphocyte (show AKAP17A Antibodies) populations.
NF-kappaB (show NFKB1 Antibodies) activity and keratinocyte differentiation are regulated by the RIP4 protein, which has roles in cutaneous wound repair
The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.
ankyrin repeat domain 3
, protein kinase PKK
, receptor-interacting serine/threonine-protein kinase 4
, receptor-interacting serine-threonine kinase 4
, receptor-interacting serine/threonine-protein kinase 4-like
, PKC-delta-interacting protein kinase
, ankyrin repeat domain-containing protein 3
, protein kinase C-associated kinase
, serine/threonine-protein kinase ANKRD3
, PKC-associated protein kinase
, PKC-regulated protein kinase