anti-Secretory Leukocyte Peptidase Inhibitor (SLPI) Antibodies

SLPI encodes a secreted inhibitor which protects epithelial tissues from serine proteases. Additionally we are shipping SLPI Kits (46) and SLPI Proteins (16) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLPI 6590 P03973
SLPI 20568 P97430
SLPI 84386  
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Top anti-SLPI Antibodies at antibodies-online.com

Showing 10 out of 113 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB <b>WB Suggested Anti-SLPI Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Human heart WB Suggested Anti-SLPI <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Biotin EIA, IHC (fro), IHC (p), WB 50 μg Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB   100 μg Log in to see 4 to 6 Days
$280.00
Details
Mouse Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 12 to 15 Days
$469.32
Details
Human Rabbit Un-conjugated WB SLPI Antibody (Center)  western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SLPI antibody detected the SLPI protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, IHC (fro), IHC (p), IP, WB 0.1 mg Log in to see 6 to 8 Days
$632.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 10 to 12 Days
$469.32
Details
Mouse Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 15 to 19 Days
$511.06
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$511.06
Details
Human Goat Un-conjugated ELISA, IHC (p), Neut, WB Immunohistochemistry-Paraffin: SLPI Antibody [NBP1-40032] - Analysis of anti-SLPI antibody with human placenta at concentration 2.5 ug/ml. Immunohistochemistry-Paraffin: SLPI Antibody [NBP1-40032] - Analysis of anti-SLPI antibody with human small intestine at concentration 2.5 ug/ml. 0.05 mg Log in to see 7 to 9 Days
$490.19
Details

SLPI Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine)


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Rat (Rattus)
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Top referenced anti-SLPI Antibodies

  1. Human Monoclonal SLPI Primary Antibody for FACS, IP - ABIN2191907 : Wingens, van Bergen, Hiemstra, Meis, van Vlijmen-Willems, Zeeuwen, Mulder, Kramps, van Ruissen, Schalkwijk: Induction of SLPI (ALP/HUSI-I) in epidermal keratinocytes. in The Journal of investigative dermatology 1999 (PubMed)
    Show all 6 Pubmed References

  2. Human Monoclonal SLPI Primary Antibody for FACS, IP - ABIN2191906 : Nakao, Hanada, Asano, Hara, Abdus Salam, Matin, Shimazu, Nakasone, Horibata, Aoba, Honda, Amagasa, Senpuku: Assessment of oral transmission using cell-free human immunodeficiency virus-1 in mice reconstituted with human peripheral blood leucocyte. in Immunology 2003 (PubMed)
    Show all 6 Pubmed References

  3. Mouse (Murine) Polyclonal SLPI Primary Antibody for ELISA, WB - ABIN1003159 : Abe, Kobayashi, Yoshimura, Trapnell, Kim, Hubbard, Brewer, Thompson, Crystal: Expression of the secretory leukoprotease inhibitor gene in epithelial cells. in The Journal of clinical investigation 1991 (PubMed)
    Show all 4 Pubmed References

  4. Human Polyclonal SLPI Primary Antibody for IHC, ELISA - ABIN1003158 : Jana, Gray, Shugars: Human immunodeficiency virus type 1 stimulates the expression and production of secretory leukocyte protease inhibitor (SLPI) in oral epithelial cells: a role for SLPI in innate mucosal immunity. in Journal of virology 2005 (PubMed)
    Show all 4 Pubmed References

More Antibodies against SLPI Interaction Partners

Human Secretory Leukocyte Peptidase Inhibitor (SLPI) interaction partners

  1. the patients with systemic sclerosis had significantly increased serum levels of SLPI in comparison with the rheumatoid arthritis patients and the healthy controls

  2. gene expression profiling study based on microarray data for the three cell types identified a number of candidates, including LCP1 (show LCP1 Antibodies) and GLI (show GLI1 Antibodies), that could be key molecules in the mechanism of SLPI-induced cell migration

  3. we show that SLPI acts as a key mediator in regulating the function of hepatic myeloid cells, to promote resolution responses through induction of MerTK (show MERTK Antibodies) expression within the resident macrophage population.

  4. these data demonstrate increased anti-inflammatory activity of the SLPI-A16G protein compared with SLPI-WT in a murine model of pulmonary Pseudomonas infection

  5. we demonstrated that the oncogenic effect of SLPI may be due to protection of growth factor progranulin (show GRN Antibodies) from enzymatic cleavage or suppression of castration-resistant prostate cancer (CRPC)cell apoptosis independent of anti-protease activity of SLPI. These findings implicate SLPI as a potential biomarker of resistance to AR inhibition and therapeutic target for CRPC treatment

  6. Secretory leukocyte protease inhibitor mediates invasiveness of oral carcinoma cells.

  7. The results indicate that SERPINE2 (show SERPINE2 Antibodies) and SLPI play a significant role in the development of papillary thyroid cancer and imply that the evaluation of serum concentrations of both anticoagulant molecules may be considered as additional marker for the differentiation of malignancies during the preoperative diagnosis of patients with thyroid gland tumors.

  8. Bronchial epithelial cells have decreased SLPI expression in response to hypoxia.

  9. Ongoing herpes simplex virus infection and resultant downregulation of local levels of SLPI may impart a greater susceptibility for keratinocytes to human papillomavirus type 16 infection through the host cell receptor annexin A2 (show ANXA2 Antibodies).

  10. SLPI is an independent predictor for both OS and DSS (show NR0B1 Antibodies) and a relevant prognostic biomarker in OSCC.

Mouse (Murine) Secretory Leukocyte Peptidase Inhibitor (SLPI) interaction partners

  1. We demonstrate by silencing the SLPI gene, that SLPI negatively regulates human periodontal ligament cell expression of the pro-inflammatory cytokines IL-6 (show IL6 Antibodies) and MCP-1 (show CPT1B Antibodies).

  2. MIF-2 (show HSPA5 Antibodies)/D-DT is an early response cytokine in the I/R injury repair of the proximal tubule, enhancing regeneration through SLPI- and ATF4 (show ATF4 Antibodies)-dependent mechanisms.

  3. Slpi(-/-) mice had impaired collagen gene expression but animals demonstrated minimal reduction in lung fibrosis compared with wild-type animals. These data suggest that enhanced proteolysis does not further enhance TGF-beta (show TGFB1 Antibodies) activation, and inhibits sustained Col1alpha1, Col3alpha1, and Col4alpha1 gene expression following lung injury.

  4. Data show that differentiative switches between bronchiolar progenitors and club cells are under the Nrf2 (show NFE2L2 Antibodies)-mediated control of SLPI and syndecan 4 (show SDC4 Antibodies).

  5. study identifies a distinct immune response in SA characterized by a dysregulated IFN-gamma (show IFNG Antibodies)/SLPI axis that affects lung function.

  6. Studied the function of Secretory Leukocyte Protease Inhibitor (SLPI) in odontoblast during mouse tooth development.

  7. Data show that the expression of several genes encoding salivary antimicrobial proteins, such as secretory leukocyte peptidase inhibitor (SLPI), S100A8 (show S100A8 Antibodies), and lactotransferrin (show LTF Antibodies), was reduced due to myeloid differentiation dactor 88 (MyD88 (show MYD88 Antibodies)) deficiency.

  8. a possible role for SLPI in enhancing the metastatic behavior of breast cancer cell line 4T1

  9. These studies define an important role for SLPI in innate and adaptive immunity and offer new insight into strategies for the use of this naturally occurring molecule in the modulation of infectious and inflammatory diseases.

  10. In experimental autoimmune encephalomyelitis, SLPI exerts potent pro-inflammatory actions by modulation of T-cell activity

SLPI Antigen Profile

Protein Summary

This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes\; the protein is also thought to have broad-spectrum anti-biotic activity.

Gene names and symbols associated with SLPI

  • secretory leukocyte peptidase inhibitor (SLPI) antibody
  • secretory leukocyte peptidase inhibitor (Slpi) antibody
  • ALK1 antibody
  • ALP antibody
  • BLPI antibody
  • ckpi antibody
  • HUSI antibody
  • HUSI-I antibody
  • MATN4 antibody
  • MPI antibody
  • SLPI antibody
  • WAP4 antibody
  • WFDC4 antibody

Protein level used designations for SLPI

HUSI-1 , WAP four-disulfide core domain protein 4 , antileukoproteinase , mucus proteinase inhibitor , protease inhibitor WAP4 , secretory leukocyte protease inhibitor (antileukoproteinase) , seminal proteinase inhibitor , ALP , secretory leukocyte protease inhibitor , matrilin 4 , secretory leukocyte peptidase inhibitor

GENE ID SPECIES
6590 Homo sapiens
20568 Mus musculus
84386 Rattus norvegicus
396886 Sus scrofa
504598 Bos taurus
641306 Ovis aries
711156 Macaca mulatta
740668 Pan troglodytes
100127207 Canis lupus familiaris
100137514 Papio anubis
100137521 Pongo abelii
100722975 Cavia porcellus
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