anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) Antibodies

The protein encoded by TNFSF14 is a member of the tumor necrosis factor (TNF) ligand family. Additionally we are shipping TNFSF14 Kits (47) and TNFSF14 Proteins (42) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNFSF14 8740 O43557
TNFSF14 301133  
TNFSF14 50930 Q9QYH9
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Top anti-TNFSF14 Antibodies at antibodies-online.com

Showing 10 out of 206 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, IF, WB   100 μg Log in to see 6 to 7 Days
$429.62
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-TNFSF14 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  721_B cell lysate TNFSF14 is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD258 expression in HeLa (A), Raw264.7 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse PE FACS Detection of LIGHT/TNFSF14 in Human CD3+ T cells by Flow Cytometry. Human CD3+ T cells treated with 1 ng/mL PMA and 1 ug/mL Calcium Ionomycin for 36 hours were stained with Mouse Anti-Human LIGHT/TNFSF14 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$357.65
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Mouse Rabbit Un-conjugated ELISA, WB Western blot analysis of LIGHT  using anti-LIGHT  antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane 1: mouse spleen tissue lysates, Lane 2: mouse cardiac muscle tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-LIGHT  antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 ug/mL overnight at 4℃, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for LIGHT  at approximately 26KD. The expected band size for LIGHT  is at 26KD. 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated ELISA, IHC, IP, WB Immunoperoxidase of monoclonal antibody to TNFSF14 on formalin-fixed paraffin-embedded human spleen (antibody concentration 3 µg/mL).  Detection limit for recombinant GST tagged TNFSF14 is approximately 1 ng/mL as a capture antibody. 100 μg Log in to see 8 to 11 Days
$461.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin-embedded: rat spleen tissue labeled with Rabbit Anti-TNFSF14 Polyclonal Antibody, Unconjugated (ABIN740625) 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin-embedded mouse liver tissue labeled with Rabbit Anti-TNFSF14 Polyclonal Antibody, Unconjugated (ABIN740625) 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$306.90
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Human Lung Tissue. 100 μg Log in to see 15 to 18 Days
$316.00
Details
Human Mouse Un-conjugated ELISA, IHC, IHC (p), IP, WB 100 μg Log in to see 7 to 9 Days
$537.17
Details

Top referenced anti-TNFSF14 Antibodies

  1. Human Monoclonal TNFSF14 Primary Antibody for FACS - ABIN4897779 : Celik, Langer, Stellos, May, Shankar, Kurz, Katus, Gawaz, Dengler: Platelet-associated LIGHT (TNFSF14) mediates adhesion of platelets to human vascular endothelium. in Thrombosis and haemostasis 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal TNFSF14 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4900484 : Wang, Wen, Routy, Bernard, Sekaly, Watts et al.: 4-1BBL induces TNF receptor-associated factor 1-dependent Bim modulation in human T cells and is a critical component in the costimulation-dependent rescue of functionally impaired HIV-specific CD8 T ... in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal TNFSF14 Primary Antibody for ELISA, WB - ABIN4330966 : Cohavy, Zhou, Ware, Targan: LIGHT is constitutively expressed on T and NK cells in the human gut and can be induced by CD2-mediated signaling. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)

  4. Human Monoclonal TNFSF14 Primary Antibody for FACS - ABIN4897778 : Holmes, Wilson, Black, Benest, Vaz, Tan, Tanavde, Cook: Licensed human natural killer cells aid dendritic cell maturation via TNFSF14/LIGHT. in Proceedings of the National Academy of Sciences of the United States of America 2014 (PubMed)

More Antibodies against TNFSF14 Interaction Partners

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) interaction partners

  1. LIGHT is highly expressed and companied with severe inflammations in patients with coronary disease. LIGHT significantly enhanced inflammation response in oxLDL-induced THP-1 (show GLI2 Antibodies) macrophages.

  2. LIGHT and LTBR (show LTBR Antibodies) interaction increases the survival and proliferation of human bone marrow-derived mesenchymal stem cells, and therefore, LIGHT might play an important role in stem cell therapy.

  3. LIGHT, via LTbetaR signaling, may contribute to exacerbation of airway neutrophilic inflammation through cytokine and chemokine (show CCL1 Antibodies) production by bronchial epithelial cells.

  4. LIGHT controls TSLP (show TSLP Antibodies) to drive pulmonary fibrosis.

  5. The tumor necrosis factor (show TNF Antibodies) superfamily molecule LIGHT promotes keratinocyte activity and skin fibrosis.

  6. proliferation and migration would be enhanced in Tca8113 cells with over-expressed TNFSF14

  7. LIGHT, a TNF (show TNF Antibodies) superfamily member, is involved in T-cell homeostasis and erosive bone disease associated with rheumatoid arthritis.

  8. Crystal structures of LIGHT and the LIGHT:DcR3 complex reveal the structural basis for the DcR3 (show TNFRSF6B Antibodies)-mediated neutralization of LIGHT.

  9. regulation by NK cell licensing helps to safeguard against TNFSF14 production in response to healthy tissues.

  10. TNFSF14 has an effect on the activation of basophils and eosinophils interacting with bronchial epithelial cells

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) interaction partners

  1. Blockade of LIGHT markedly suppressed airway smooth muscle hyperplasia and inflammatory responses, which might be modulated through HVEM (show TNFRSF14 Antibodies)-NFkappaB or c-JUN (show JUN Antibodies) pathways.

  2. The LIGHT (Tumour necrosis factor (show TNF Antibodies) ligand superfamily member 14, TNFSF14)/Lymphotoxin beta-Receptor (show LTBR Antibodies)(LTbeta (show LTB Antibodies)-R) pathway, which is involved in T-cell and macrophage activation, was diminished in plasma and in apoE (show APOE Antibodies)-/-Irs2 (show IRS2 Antibodies)+/-HL-/- atheromas.

  3. LIGHT signalling pathway combined with IFN-gamma (show IFNG Antibodies) induces beta cells apoptosis via an NF-kappaB (show NFKB1 Antibodies)/Bcl2 (show BCL2 Antibodies)-dependent mitochondrial pathway.

  4. Together, these results demonstrate that the LIGHT signaling pathway is not only required for inflammatory cytokine production as part of the host response to chlamydial infection, but also influences the differentiation of CD4 (show CD4 Antibodies)(+) CD25 (show IL2RA Antibodies)(+) FoxP3 (show FOXP3 Antibodies)(+) Treg cells, both of which may be essential for control of C. psittaci respiratory tract infection.

  5. These results expose the relevance of LIGHT/LTbetaR/HVEM (show TNFRSF14 Antibodies) interaction for the potential therapeutic control of the allogeneic immune responses mediated by alloreactive CD8 (show CD8A Antibodies) T cells that can contribute to prolong allograft survival.

  6. Mechanistically, intratumoral LIGHT induces pericyte differentiation and normalization via Rho kinase (show ROCK2 Antibodies) signaling. Minute amounts of LIGHT act in a paracrine fashion to trigger an amplifying cascade involving transforming growth factor beta (TGF-beta) from peri (show POSTN Antibodies)-vascular macrophages.

  7. localized overexpression of Tnfsf14 potently enhances muscle regeneration, and that this regenerative capacity of Tnfsf14 is dependent on Akt (show AKT1 Antibodies) signaling.

  8. LIGHT-HVEM (show TNFRSF14 Antibodies) interactions stimulate IL-12 (show IL12A Antibodies) production by DCs during Leishmania donovani infection. Blockade of LIGHT-LTbetaR interactions dramatically enhanced early anti-parasitic immunity.

  9. LIGHT controls TSLP (show TSLP Antibodies) to drive pulmonary fibrosis.

  10. The tumor necrosis factor (show TNF Antibodies) superfamily molecule LIGHT promotes keratinocyte activity and skin fibrosis.

TNFSF14 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

Gene names and symbols associated with TNFSF14

  • TNF superfamily member 14 (TNFSF14) antibody
  • TNF superfamily member 14 (Tnfsf14) antibody
  • tumor necrosis factor (ligand) superfamily, member 14 (Tnfsf14) antibody
  • CD258 antibody
  • HVEM-L antibody
  • HVEML antibody
  • LIGHT antibody
  • LTg antibody
  • Ly113 antibody
  • TNFSF14 antibody
  • TR2 antibody

Protein level used designations for TNFSF14

tumor necrosis factor ligand superfamily, member 14 , tumor necrosis factor (ligand) superfamily, member 14 , delta transmembrane LIGHT , herpes virus entry mediator ligand , herpesvirus entry mediator A , herpesvirus entry mediator ligand , herpesvirus entry mediator-ligand , ligand for herpesvirus entry mediator , tumor necrosis factor ligand superfamily member 14 , tumor necrosis factor receptor-like 2 , tumor necrosis factor superfamily member LIGHT , tumor necrosis factor superfamily member 14 , tumor necrosis factor superfamily, member 14

GENE ID SPECIES
468687 Pan troglodytes
701451 Macaca mulatta
8740 Homo sapiens
301133 Rattus norvegicus
611306 Canis lupus familiaris
100519468 Sus scrofa
505521 Bos taurus
50930 Mus musculus
100347876 Oryctolagus cuniculus
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