serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Proteins (SERPINA3)

The protein encoded by SERPINA3 is a plasma protease inhibitor and member of the serine protease inhibitor class. Additionally we are shipping serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Antibodies (342) and serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Kits (46) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SERPINA3 12 P01011
Rat SERPINA3 SERPINA3 24648 P17475
SERPINA3    
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Top serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Proteins at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Human Cells Human His tag 10 μg Log in to see 20 to 21 Days
$250.80
Details
HEK-293 Cells Human His tag Human Serpin A3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 50 μg Log in to see 2 to 3 Days
$346.50
Details
HEK-293 Cells Human His tag 10 μg Log in to see 2 to 3 Days
$220.00
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$286.00
Details
Human Human Un-conjugated   1 mg Log in to see 6 to 7 Days
$371.07
Details
Yeast Orang-Utan His tag   1 mg Log in to see 60 to 71 Days
$3,107.50
Details
HEK-293 Cells Human His tag   0.05 mg Log in to see 2 to 3 Days
$618.75
Details
Human Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$95.00
Details
Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 15 to 18 Days
$416.00
Details

SERPINA3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, ,
Mouse (Murine)

Top referenced serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Proteins

  1. Human SERPINA3 Protein expressed in Human - ABIN3119637 : Ungurs, Sinden, Stockley: Progranulin is a substrate for neutrophil-elastase and proteinase-3 in the airway and its concentration correlates with mediators of airway inflammation in COPD. in American journal of physiology. Lung cellular and molecular physiology 2014 (PubMed)
    Show all 8 Pubmed References

More Proteins for serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) Interaction Partners

Human serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) interaction partners

  1. evaluation of serum proteins reveals that SERPINA1 (show SERPINA1 Proteins), SERPINA3 and SERPINC1 (show SERPINC1 Proteins) could be useful to discriminate healthy from colorectal carcinoma patients with a high sensitivity and specificity

  2. This study confirms the prognostic potential of SERPINA3 expression in human cutaneous melanoma

  3. AACT is downregulated in NSCLC. The GlcNAcylated AACT can effectively differentiate Stage I non-small cell lung cancer from healthy or benign lung disease samples.

  4. The ACT gene (also named SERPINA3) was mapped on chromosome 14q32.1 We studied the association between Alpha-1 antichymotrypsin (ACT) signal peptide A/T polymorphism polymorphism and risk of primary intracerebral hemorrhage

  5. Proteome demonstration of alpha-1-acid glycoprotein (show ORM1 Proteins) and alpha-1-antichymotrypsin candidate biomarkers for diagnosis of enterovirus 71 infection

  6. SERPINA3 promotes endometrial cancer cells growth by regulating G2/M cell cycle checkpoint and apoptosis.

  7. This study demonistrated that SERPINA3 is changed in the dorsolateral prefrontal cortex of individuals with schizophrenia

  8. Prostate specific antigen (PSA) forms complexes with alpha1-antichymotrypsin (ACT) within the prostate, which may explain, at least partially, why the ratio of serum PSA-ACT to total PSA is increased in prostate cancer.

  9. the promoter of SERPINA3 is transcriptionally activated by three transcription factors (SP1 (show PSG1 Proteins), MZF1 (show ZFP42 Proteins) and ZBTB7B (show ZBTB7B Proteins))

  10. The common alpha1-antichymotrypsin signal peptide -15A/T polymorphism may not be a major risk factor for Alzheimer disease (AD) but the polymorphism is capable of increasing late onset AD risk. [Meta-analysis]

Horse (Equine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) interaction partners

  1. Although circulating nucleosomes and elastase - alpha 1-antitrypsin (show SERPINA1 Proteins) complexes are at present the best characterized biomarkers for neutrophil extracellular traps formation and neutrophil activation, their lack of association with rs2288904 genotype does not exclude a role for SLC44A2 (show SLC44A2 Proteins) in neutrophil activation (and possibly NET formation) in Venous Thromboembolism.

serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) Protein Profile

Protein Summary

The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Gene names and symbols associated with SERPINA3

  • serpin A3-5 (LOC396684)
  • serpin family A member 3 (SERPINA3)
  • alpha-1-antiproteinase F precursor (LOC100008973)
  • alpha-1-antitrypsin (SPI2)
  • serpin family A member 1 (SERPINA1)
  • serpin family A member 1 (Serpina1)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 (SPIA5)
  • SH2B adaptor protein 2 (Sh2b2)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 L homeolog (serpina3.L)
  • A1AT protein
  • AACT protein
  • AAT protein
  • ACT protein
  • alpha-1-PI protein
  • Aps protein
  • GIG25 protein
  • Pi protein
  • Pi2 protein
  • serpina3 protein
  • SERPINA3-1 protein
  • SERPINA3-5 protein
  • Spi1 protein

Protein level used designations for SERPINA3

alpha-1-antichymotrypsin 1 , alpha-1-antichymotrypsin , cell growth-inhibiting gene 24/25 protein , growth-inhibiting protein 24 , growth-inhibiting protein 25 , serine (or cysteine) proteinase inhibitor, clade A, member 3 , serpin A3 , ACT , APF , alpha-1-antiproteinase F , alpha-1-antitrypsin , alpha-1-proteinase inhibitor , alpha-1-antiproteinase 2 , alpha-1-antitrypsin 2 , alpha-1-proteinase inhibitor 2 , alpha-1 antitrypsin , alpha-1-antiproteinase , protease inhibitor 1 , serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1 , alpha-1-antitrypsin (protease inhibitor) , alpha-1-protease inhibitor , serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 , serine (or cysteine) proteinase inhibitor, clade A, member 1 , serine protease inhibitor alpha 1 , serpin A1 , alpha-1 protease inhibitor , alpha-1-antiproteinase S , alpha 1 antitrypsin , serpin A3-5 , serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 L homeolog

GENE ID SPECIES
396684 Sus scrofa
12 Homo sapiens
100173860 Pongo abelii
100008973 Oryctolagus cuniculus
100065158 Equus caballus
443388 Ovis aries
24648 Rattus norvegicus
397688 Sus scrofa
423435 Gallus gallus
100379265 Cavia porcellus
480422 Canis lupus familiaris
617667 Bos taurus
495377 Xenopus laevis
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