anti-Human NOD1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended NOD1 Antibody (supplied by: Log in to see )

Antigen
Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) Antibodies
  • CARD4
  • CLR7.1
  • NLRC1
  • C230079P11
  • Card4
  • F830007N14Rik
  • Nlrc1
  • RGD1562269
  • nucleotide binding oligomerization domain containing 1
  • nucleotide-binding oligomerization domain containing 1
  • NOD1
  • Nod1
Epitope
AA 64-105
29
17
11
8
7
7
5
5
4
3
3
3
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
120
47
26
1
1
1
1
Host
Rabbit
116
16
6
Clonality
Polyclonal
Conjugate
This NOD1 antibody is un-conjugated
6
6
5
5
5
5
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
131
68
31
24
10
8
7
6
4
4
2
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Catalog No. ABIN872332
$ 329.45
Plus shipping costs $45.00

General

Antigen Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) Antibodies
Epitope AA 64-105
(29), (17), (11), (8), (7), (7), (5), (5), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(120), (47), (26), (1), (1), (1), (1)
Host Rabbit
(116), (16), (6)
Clonality
Polyclonal
Conjugate This NOD1 antibody is un-conjugated
(6), (6), (5), (5), (5), (5)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(131), (68), (31), (24), (10), (8), (7), (6), (4), (4), (2)
Pubmed 1 reference available
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Product Details anti-NOD1 Antibody

Target Details NOD1 Application Details Handling References for anti-NOD1 antibody (ABIN872332) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human CARD4
Isotype IgG
Plasmids, Primers & others

Target Details NOD1

Product Details anti-NOD1 Antibody Application Details Handling References for anti-NOD1 antibody (ABIN872332) Images back to top
Antigen
Alternative Name Card4 (NOD1 Antibody Abstract)
Background

Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Required for RHOA and RIPK2 dependent NF-kappa-B signaling pathway activation upon S.flexneri cell invasion. Involved not only in sensing peptidoglycan (PGN)-derived muropeptides but also in the activation of NF-kappa-B by Shigella effector proteins IpgB2 and OspB. Recruits NLRP10 to the cell membrane following bacterial infection.

Subcellular location: Helical

Synonyms: CARD4, NLRC1, CLR7.1, Nucleotide-binding oligomerization domain-containing protein 1, Caspase recruitment domain-containing protein 4, NOD1

Gene ID 10392
UniProt Q9Y239
Pathways Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades

Application Details

Product Details anti-NOD1 Antibody Target Details NOD1 Handling References for anti-NOD1 antibody (ABIN872332) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-NOD1 Antibody Target Details NOD1 Application Details References for anti-NOD1 antibody (ABIN872332) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-NOD1 antibody (ABIN872332)

Product Details anti-NOD1 Antibody Target Details NOD1 Application Details Handling Images back to top
Product cited in:

Arentsen, Qian, Gkotzis, Femenia, Wang, Udekwu, Forssberg, Diaz Heijtz: "The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior." in: Molecular psychiatry, Vol. 22, Issue 2, pp. 257-266, 2016 Method employed by authors: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Frozen Sections) (IHC (fro)) (Sample species: Mouse (Murine)). Further details: Sample: brain

Images

Product Details anti-NOD1 Antibody Target Details NOD1 Application Details Handling References for anti-NOD1 antibody (ABIN872332) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 64-105) antibody (ABIN872332) Formalin-fixed and paraffin embedded human placenta labeled with Rabbit Anti CARD4 Po...
Immunohistochemistry (IHC) image for anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 64-105) antibody (ABIN872332) Formalin-fixed and paraffin embedded mouse spleen labeled with Rabbit Anti CARD4 Poly...
Immunohistochemistry (IHC) image for anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 64-105) antibody (ABIN872332) Formalin-fixed and paraffin embedded rat lung labeled with Rabbit Anti CARD4 Polyclon...