beta-2 Microglobulin antibody
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- Target See all beta-2 Microglobulin (B2M) Antibodies
- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This beta-2 Microglobulin antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Specificity
- Specific for B2M denatured and native forms
- Cross-Reactivity
- Human
- Purification
- Protein G purified
- Purity
- > 95 %
- Immunogen
- Recombinant human Beta-2-microglobulin protein
- Clone
- 2D3E5
- Isotype
- IgG1, IgG1 kappa
- Top Product
- Discover our top product B2M Primary Antibody
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- Application Notes
- Recommended dilution:IHC:1:50-1:500,
- Comment
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Other species are not tested. Please decide the specificity by homology
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid freeze and thaw cycles.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Beta2-microglobulin and alpha1-microglobulin as markers of Balkan endemic nephropathy, a worldwide disease." in: Renal failure, Vol. 33, Issue 2, pp. 176-83, (2011) (PubMed).
: "Evaluating percutaneous nephrolithotomy-induced kidney damage by measuring urinary concentrations of β2-microglobulin." in: Urology journal, Vol. 8, Issue 4, pp. 277-82, (2011) (PubMed).
: "Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods." in: Proteomics. Clinical applications, Vol. 5, Issue 7-8, pp. 422-31, (2011) (PubMed).
: "β2-microglobulin, a novel biomarker of peripheral arterial disease, independently predicts aortic stiffness in these patients." in: Scandinavian journal of clinical and laboratory investigation, Vol. 71, Issue 4, pp. 257-63, (2011) (PubMed).
: "Urinary clusterin, cystatin C, beta2-microglobulin and total protein as markers to detect drug-induced kidney injury." in: Nature biotechnology, Vol. 28, Issue 5, pp. 463-9, (2010) (PubMed).
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Beta2-microglobulin and alpha1-microglobulin as markers of Balkan endemic nephropathy, a worldwide disease." in: Renal failure, Vol. 33, Issue 2, pp. 176-83, (2011) (PubMed).
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- Target
- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
- Alternative Name
- B2M (B2M Products)
- Synonyms
- Ly-m11 antibody, beta2-m antibody, beta2m antibody, bwm antibody, wu:fa94c05 antibody, wu:fb10a09 antibody, b2m-W01 antibody, b2m-W03 antibody, b2m-Z01 antibody, b2m-Z02 antibody, b2m-Z03 antibody, B2M antibody, b2m antibody, B2MG antibody, wu:fb66f11 antibody, wu:fj01f08 antibody, zgc:64161 antibody, b-2-m antibody, beta-2-microglobulin antibody, beta-2 microglobulin antibody, beta-2-microglobulin S homeolog antibody, beta-2-microglobulin, like antibody, B2M antibody, B2m antibody, b2m antibody, b2m.S antibody, b2ml antibody
- Background
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Background: Beta 2 Microglobulin non-covalently associates with the 44 kDa alpha chain to form the HLA Class I antigen complex. Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.
Aliases: B2M, CDABP0092, HDCMA22P
- UniProt
- P61769
- Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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