SCN9A antibody (AA 1874-1887)

Catalog No. ABIN1104142

Product Details anti-SCN9A Antibody

Target: SCN9A (Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))

Binding Specificity: AA 1874-1887

Reactivity: Human, Monkey, Dog, Guinea Pig, Horse, Rabbit, Bat, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This SCN9A antibody is un-conjugated

Application: ELISA

Specificity: Human SCN9A / Nav1.7.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Gibbon, Monkey, Marmoset, Elephant, Panda, Bovine, Bat, Dog, Horse, Rabbit, Porcine, Guinea pig (100%) Galago, Mouse, Hamster, Lizard (93%) Rat, Opossum, Chicken, Platypus (86%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-KRKQEDVSATVIQR from an internal region (near C-terminus) of human SCN9A / Nav1.7 (NP_002968.1). Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Gibbon, Monkey, Marmoset, Elephant, Panda, Bovine, Bat, Dog, Horse, Rabbit, Porcine, Guinea pig (100%), Galago, Mouse, Hamster, Lizard (93%), Rat, Opossum, Chicken, Platypus (86%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:64000)

Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Preliminary experiments gave an approx 80kD band in Human Brain (Cerebellum), Mouse brain and Rat Ovary lysates after 0.1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 225kD according to NP_002968.1. The 80kD band was successfully blocked by incubation with the immunizing peptide.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for SCN9A

Target: SCN9A (Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))

Alternative Name: SCN9A / Nav1.7 (SCN9A Products)

Synonyms: SCN9A antibody, DKFZp459G084 antibody, Nav1.7 antibody, PN1 antibody, mKIAA4197 antibody, Scn2a antibody, ETHA antibody, FEB3B antibody, GEFSP7 antibody, NE-NA antibody, NENA antibody, SFNP antibody, sodium channel, voltage-gated, type IX, alpha subunit antibody, sodium voltage-gated channel alpha subunit 9 antibody, sodium channel protein type 9 subunit alpha antibody, sodium channel, voltage-gated, type IX, alpha antibody, SCN9A antibody, LOC100016648 antibody, Scn9a antibody

Background: Name/Gene ID: SCN9A
Subfamily: Sodium channel - voltage-gated
Family: Ion Channel

Synonyms: SCN9A, ETHA, GEFSP7, Nav1.7, HNE-Na, Peripheral sodium channel 1, PN1, SFNP, Sodium channel 25, Neuroendocrine sodium channel, FEB3B, NE-NA, NENA

Gene ID: 6335

NCBI Accession: NP_002968

UniProt: Q15858