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CACNA1C antibody (C-Term)
CACNA1C
Reactivity: Human
WB, EIA, IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CACNA1C Antibody
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Target
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CACNA1C
(Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))
Binding Specificity
All epitopes for CACNA1C antibodies
C-Term
Reactivity
All reactivities for CACNA1C antibodies
Human
Host
All hosts for CACNA1C antibodies
Rabbit
Clonality
All clonalities for CACNA1C antibodies
Polyclonal
Conjugate
All conjugates for CACNA1C antibodies
This CACNA1C antibody is un-conjugated
Application
All applications for CACNA1C antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
Specificity
Reacts with Human 248 kDa CACNA1C protein. May cross react with Rat, Mouse and other species.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Affinity Chromatography on Protein A
Immunogen
Synthetic peptide derived from C-terminal domain of CAC1C protein.
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Discover our top product CACNA1C Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Reconstitution
Restore in distilled water.
Buffer
0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for CACNA1C
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Target
CACNA1C
(Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))
Alternative Name
CACNA1C (CACNA1C Products )
Synonyms
CACH2 antibody, CACN2 antibody, CACNL1A1 antibody, CCHL1A1 antibody, CaV1.2 antibody, LQT8 antibody, TS antibody, Cav1.2 antibody, Cchl1a1 antibody, MBC antibody, MELC-CC antibody, RATIVS302 antibody, isl antibody, C-LTCC antibody, CHCACHA1C antibody, ICA antibody, cav1.2 antibody, ca(v)1.2 antibody, CAV1.2 antibody, BCR antibody, rbc antibody, calcium voltage-gated channel subunit alpha1 C antibody, calcium channel, voltage-dependent, L type, alpha 1C subunit antibody, voltage-dependent L-type calcium channel subunit alpha-1C antibody, calcium channel, voltage-dependent, L type, alpha 1C subunit S homeolog antibody, Red blood cell count antibody, RNA, 7SL, cytoplasmic 263, pseudogene antibody, CACNA1C antibody, Cacna1c antibody, cacna1c antibody, LOC100442085 antibody, cacna1c.S antibody, RBC antibody, RN7SL263P antibody
Background
CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by CACNA1C binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins.Synonyms: CACH2, CACN2, CACNL1A1, CCHL1A1, Calcium channel L type alpha-1 polypeptide isoform 1 cardiac muscle, Cav1.2, Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-gated calcium channel subunit alpha
Gene ID
775
NCBI Accession
NP_000710
Pathways
Hormone Transport , Carbohydrate Homeostasis
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