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ERK2 antibody (N-Term)
MAPK1
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ERK2 Antibody
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Target
See all ERK2 (MAPK1) Antibodies
ERK2 (MAPK1)
(Mitogen-Activated Protein Kinase 1 (MAPK1))
Binding Specificity
All epitopes for ERK2 antibodies
N-Term
Reactivity
All reactivities for ERK2 antibodies
Human, Mouse, Rat
Host
All hosts for ERK2 antibodies
Rabbit
Clonality
All clonalities for ERK2 antibodies
Polyclonal
Conjugate
All conjugates for ERK2 antibodies
This ERK2 antibody is un-conjugated
Application
All applications for ERK2 antibodies
Western Blotting (WB)
Specificity
This antibody detects ERK2 (N-term). No cross reactivity with other proteins.
Cross-Reactivity (Details)
Species reactivity (expected):Mouse, ratSpecies reactivity (tested):Human
Purification
Immunogen affinity purified
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminal of human ERK2 .Remarks: Sequence is identical to the related rat and mouse sequence.
Isotype
IgG
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Discover our top product MAPK1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Reconstitution
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer
5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
Preservative
Sodium azide, Thimerosal (Merthiolate)
Precaution of Use
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target Details for ERK2
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Target
ERK2 (MAPK1)
(Mitogen-Activated Protein Kinase 1 (MAPK1))
Alternative Name
ERK2 (MAPK1 Products )
Synonyms
ERK-1 antibody, ERK1 antibody, ERT2 antibody, HS44KDAP antibody, HUMKER1A antibody, P44ERK1 antibody, P44MAPK antibody, PRKM3 antibody, p44-ERK1 antibody, p44-MAPK antibody, Erk-1 antibody, Erk1 antibody, Ert2 antibody, Esrk1 antibody, Mnk1 antibody, Mtap2k antibody, Prkm3 antibody, p44 antibody, p44erk1 antibody, p44mapk antibody, ERK antibody, ERK2 antibody, ERT1 antibody, MAPK2 antibody, P42MAPK antibody, PRKM1 antibody, PRKM2 antibody, p38 antibody, p40 antibody, p41 antibody, p41mapk antibody, 9030612K14Rik antibody, AA407128 antibody, AU018647 antibody, C78273 antibody, Erk2 antibody, Prkm1 antibody, p42mapk antibody, zERK2 antibody, MAPK1 antibody, Xp42 antibody, erk antibody, erk2 antibody, ert1 antibody, mapk antibody, mapk1b antibody, mapk2 antibody, mpk1 antibody, prkm1 antibody, prkm2 antibody, mapk1 antibody, mapk1a antibody, xp42 antibody, ATMPK1 antibody, F14N23.9 antibody, F14N23_9 antibody, MITOGEN-ACTIVATED PROTEIN KINASE antibody, mitogen-activated protein kinase 1 antibody, MNK1 antibody, ATMPK2 antibody, MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2 antibody, T30E16.13 antibody, T30E16_13 antibody, mitogen-activated protein kinase homolog 2 antibody, mitogen-activated protein kinase 3 antibody, mitogen-activated protein kinase 1 antibody, mitogen activated protein kinase 1 antibody, mitogen-activated protein kinase 1 L homeolog antibody, mitogen-activated protein kinase 1 S homeolog antibody, mitogen activated protein kinase 3 antibody, mitogen-activated protein kinase homolog 2 antibody, MAPK3 antibody, Mapk3 antibody, MAPK1 antibody, Mapk1 antibody, mapk1 antibody, mapk1.L antibody, mapk1.S antibody, PfMAP1 antibody, MPK1 antibody, PVX_084965 antibody, LOC9328617 antibody, Tsp_01601 antibody, MPK2 antibody
Background
Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2, is an enzyme which in humans is encoded by the MAPK1 gene. The gene is mapped to 22q11.2. And The protein encoded by this gene is a member of the MAP kinase family. The deduced 360-amino acid human ERK2 protein shares 98 % identity with rat Erk2. The MAP kinase ERK2 is widely involved in eukaryotic signal transduction. Upon activation, it translocates to the nucleus of the stimulated cell, where it phosphorylates nuclear targets. Futhermore, the ERK pathway is necessary for experience-dependent plasticity and for long-term potentiation of synaptic transmission in the developing visual cortex. And the MAPK pathway is also involved in responses to NTN1.Synonyms: ERT1, Extracellular signal-regulated kinase 2, MAP kinase 2, MAPK1, MAPK2, Mitogen-activated protein kinase 1, PRKM1, PRKM2, p42-MAPK
Gene ID
5594
NCBI Accession
NP_002736
UniProt
P28482
Pathways
MAPK Signaling , RTK Signaling , Apoptosis , Interferon-gamma Pathway , Fc-epsilon Receptor Signaling Pathway , Response to Growth Hormone Stimulus , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Hepatitis C , Protein targeting to Nucleus , Toll-Like Receptors Cascades , Monocarboxylic Acid Catabolic Process , Autophagy , G-protein mediated Events , Signaling Events mediated by VEGFR1 and VEGFR2 , Signaling of Hepatocyte Growth Factor Receptor , VEGFR1 Specific Signals , BCR Signaling , S100 Proteins
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