Paired Box 3 antibody (Internal Region)
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- Target See all Paired Box 3 (PAX3) Antibodies
- Paired Box 3 (PAX3)
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat, Dog
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This Paired Box 3 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody is expected to recognize isoforms PAX3 (NP_852122.1), PAX3d (NP_852123.1), PAX3e (NP_852124.1), PAX3g (NP_852126.1), PAX3h (NP_852125.1) and PAX3i (NP_001120838.1).
- Cross-Reactivity (Details)
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Species reactivity (expected):Canine (Dog), Bovine, Porcine.
Species reactivity (tested):Human, Mouse, Rat. - Purification
- Affinity Chromatography
- Immunogen
- Peptide with sequence C-STVHQSTIPSNPD, from the internal region of the protein sequence according to NP_852122.1, NP_000429.2, NP_039230.1, NP_852123.1, NP_852124.1, NP_852126.1, NP_852125.1, NP_001120838.1. Genename: PAX3
- Top Product
- Discover our top product PAX3 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Paired Box 3 (PAX3)
- Alternative Name
- PAX3 (PAX3 Products)
- Synonyms
- PAX3 antibody, cdhs antibody, hup2 antibody, pax-3 antibody, ws1 antibody, xpax3 antibody, Pax3 antibody, pax3 antibody, pax3b antibody, xPax3-B antibody, CDHS antibody, HUP2 antibody, WS1 antibody, WS3 antibody, Pax-3 antibody, Sp antibody, splotch antibody, zgc:92547 antibody, paired box 3 antibody, paired box 3 L homeolog antibody, paired box 3a antibody, PAX3 antibody, pax3 antibody, pax3.L antibody, Pax3 antibody, pax3a antibody
- Background
- This protein is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These proteins play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.Synonyms: HUP2, Paired box protein Pax-3, Pax-3
- Molecular Weight
- 53.0 kDa (Human NP_852122.1) and 52.9 kDa (Mouse NP_032807.3)
- Gene ID
- 5077
- NCBI Accession
- NP_000429
- Pathways
- Sensory Perception of Sound, Tube Formation
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