Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Reconstitution
Add 100 μL of distilled water to a final concentration of 1 mg/mL.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.Synonyms: AML1T1, CBFA2T1, CDR, Cyclin-D-related protein, ETO, Eight twenty one protein, MTG8, ZMYND2, Zinc finger MYND domain-containing protein 2