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PIDD antibody

PIDD Reactivity: Mouse WB Host: Mouse Monoclonal Lise-1 unconjugated
Catalog No. ABIN1169269
  • Target See all PIDD Antibodies
    PIDD (P53-Induced Death Domain Protein (PIDD))
    Reactivity
    • 20
    • 20
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 34
    • 2
    Mouse
    Clonality
    • 34
    • 2
    Monoclonal
    Conjugate
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PIDD antibody is un-conjugated
    Application
    • 13
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    Recognizes mouse PIDD.
    Cross-Reactivity
    Mouse (Murine)
    Purification
    Purified from concentrated hybridoma tissue culture supernatant.
    Purity
    >95 % (SDS-PAGE)
    Immunogen
    Mouse PIDD (Death Domain).
    Clone
    Lise-1
    Isotype
    IgG2b
    Top Product
    Discover our top product PIDD Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Expiry Date
    12 months
  • Target
    PIDD (P53-Induced Death Domain Protein (PIDD))
    Alternative Name
    PIDD (PIDD Products)
    Synonyms
    1200011D09Rik antibody, AU042446 antibody, Pidd antibody, LRDD antibody, Lrdd antibody, p53 induced death domain protein 1 antibody, p53-induced death domain protein 1 antibody, Pidd1 antibody, PIDD1 antibody
    Background
    PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
    UniProt
    Q9ERV7
    Pathways
    p53 Signaling, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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