The antibody A67-B/E3 reacts with Prostate-Specific Antigen (PSA), a protein produced by normal prostate cells. The highest amounts of PSA are found in the seminal fluid.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Precipitation Methods.
Immunogen
30 KDa protein fraction prepared from human seminal plasma
Immunohistochemistry on paraffin-embedded sections (proteolytic digestion of the tissue is essential). Western Blotting: Positive material: seminal plasma. ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undilued at 2-8 °C forr one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Prostate-specific antigen (PSA) is a protein produced by normal prostate cells. This enzyme participates in the dissolution of the seminal fluid coagulum and plays an important role in fertility. The highest amounts of PSA are found in the seminal fluid, some PSA escapes the prostate and can be found in the serum. This serum component has been used to track the response to therapy in men with prostate cancer.Synonyms: Gamma-seminoprotein, P-30 antigen, Prostate-specific antigen, Semenogelase