ITGA4 antibody (FITC)

Catalog No. ABIN133852

Product Details anti-ITGA4 Antibody (FITC)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ITGA4 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Specificity: Mouse CD49d ( 4 integrin)

Purification: Purified from ascites via Protein G Chromatography

Immunogen: Peyers Patch HEV binding lymphoma line (TK1) . Fusion Partner: P3x63Ag8.653 . Donor: Fisher Spleen

Isotype: IgG2b

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.1 mg/ml

Buffer: FITC conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Alternative Name: CD49d (ITGA4 Products)

Synonyms: CD49D antibody, IA4 antibody, LOC100219853 antibody, integrin subunit alpha 4 antibody, integrin alpha 4 antibody, integrin subunit alpha 4 S homeolog antibody, ITGA4 antibody, Itga4 antibody, itga4.S antibody

Background: Anti-mouse CD49d monoclonal antibody reacts with 4 integrin, which helps to mediate cell-cell and cell-matrix interactions. 4 integrin combines with 1 and 7integrin to form VLA-4 and LPAM-1 (Peyers patch homing receptor) respectively. VLA-4 is expressed on most peripheral lymphocytes, thymocytes and monocytes. LPAM-1 is found on peripheral lymphocytes, but few thymocytes. Fibronectin and VCAM-1 act as ligands for both VLA-4 and LPAM-1. LPAM-1 also binds the mucosal vascular addressin MAdCAM-1. (1) Applications of this clone include flow cytometry, immunoprecipitation and immunohistochemistry. (1,2,3)

Pathways: Integrin Complex