CD8B antibody (Biotin)

Catalog No. ABIN133934

Product Details anti-CD8B Antibody (Biotin)

Target: CD8B (CD8b Molecule (CD8B))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD8B antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Specificity: Mouse CD8 -Chain

Purification: Ion exchange column

Isotype: IgG2a

Application Details

Application Notes: This antibody is suitable for use in flow cytometry.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/ml

Storage: 4 °C

Target Details for CD8B

Target: CD8B (CD8b Molecule (CD8B))

Alternative Name: CD8 -Chain (Ly-3) (CD8B Products)

Synonyms: Cd8b antibody, Ly-3 antibody, Ly-C antibody, Lyt-3 antibody, CD8B1 antibody, LEU2 antibody, LY3 antibody, LYT3 antibody, P37 antibody, Cd8b1 antibody, CD8b molecule antibody, CD8 antigen, beta chain 1 antibody, Cd8b antibody, CD8B antibody, Cd8b1 antibody

Background: Anti-mouse CD8 Chain monoclonal antibody reacts with the mouse CD8 chain. The CD8 Chain is also named Ly-3. The CD8 chain associates with the CD8 chain to form the CD8 / heterodimer on MHC class I restricted T-cells (cytotoxic T cells) and most thymocytes . Since a small subset of T cells (IEL cells) express CD8 / homodimers rather than CD8 / heterodimers, investigators should use an antibody directed against the CD8 chain (CL168B, clone CT-CD8a) to definitively label mouse CD8 cells. This antibody is suitable for use in flow cytometry.

Pathways: TCR Signaling