UBE2L6 antibody (AA 21-120)
-
- Target See all UBE2L6 Antibodies
- UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
-
Binding Specificity
- AA 21-120
-
Reactivity
- Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This UBE2L6 antibody is un-conjugated
-
Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Ube2L6
- Isotype
- IgG
- Top Product
- Discover our top product UBE2L6 Primary Antibody
-
-
- Application Notes
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
-
- Target
- UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
- Alternative Name
- Ube2L6 (UBE2L6 Products)
- Synonyms
- UBE2L6 antibody, RIG-B antibody, UBCH8 antibody, 2810489I21Rik antibody, Ubce8 antibody, Ubcm8 antibody, UbcM8 antibody, ubiquitin conjugating enzyme E2 L6 antibody, ubiquitin-conjugating enzyme E2L 6 antibody, UBE2L6 antibody, Ube2l6 antibody
- Background
-
Synonyms: Retinoic acid induced gene B protein, Retinoic acid-induced gene B protein, RIG B, RIG-B, UB2L6_HUMAN, UBCH 8, UBCH8, UBE2L6, Ubiquitin carrier protein, Ubiquitin carrier protein L6, Ubiquitin conjugating enzyme E2L 6, Ubiquitin protein ligase, Ubiquitin protein ligase L6, Ubiquitin-protein ligase L6, Ubiquitin/ISG15 conjugating enzyme E2 L6, Ubiquitin/ISG15-conjugating enzyme E2 L6.
Background: Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells, either free or covalently attached to cellular proteins. The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign, and improperly folded proteins by targeting them for proteosome degradation. Ubiquitin conjugating enzyme 8 (UBC8) is an E2 enzyme involved in the ubiquitin pathway for protein degradation. Like other E2 enzymes, UBC8 forms a thioester bond with ubiquitin in an E1-dependent manner. UBC8 binds to the human homolog of Drosophila ariadne (HHARI) and UBC7-associated protein (H7-AP1) as well as double ring-finger protein (Dorfin). UBC8 is enriched in the central nervous system and interacts with Parkin, a RING-finger-containing protein implicated in the pathogenesis of familial Parkinson?s disease. Parkin shares sequence homology with other UBC8 binding proteins such as HHARI and H7-AP1.
- Gene ID
- 9246
-