FOXG1 antibody (Alexa Fluor 488)

Catalog No. ABIN1391974

Product Details anti-FOXG1 Antibody (Alexa Fluor 488)

Target: FOXG1 (Forkhead Box G1 (FOXG1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXG1 antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB)

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FOXG1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FOXG1

Target: FOXG1 (Forkhead Box G1 (FOXG1))

Alternative Name: Foxg1/Bf-1 (FOXG1 Products)

Synonyms: BF-1 antibody, bf1 antibody, foxg1 antibody, zgc:109850 antibody, qin antibody, XBf1 antibody, fkh2 antibody, hfk1 antibody, XBF-1 antibody, fkhl1 antibody, fkhl4 antibody, hbf-1 antibody, foxg1b antibody, bf-1 antibody, FOXG1 antibody, BmFOXG1 antibody, zgc:85969 antibody, BF1 antibody, BF2 antibody, FHKL3 antibody, FKH2 antibody, FKHL1 antibody, FKHL2 antibody, FKHL3 antibody, FKHL4 antibody, FOXG1A antibody, FOXG1B antibody, FOXG1C antibody, HBF-1 antibody, HBF-2 antibody, HBF-3 antibody, HBF-G2 antibody, HBF2 antibody, HFK1 antibody, HFK2 antibody, HFK3 antibody, KHL2 antibody, QIN antibody, foxg1b-a antibody, 2900064B05Rik antibody, Bf1 antibody, Hfh9 antibody, Hfhbf1 antibody, BF1A antibody, Fkhl1 antibody, RATBF1A antibody, CBF-1 antibody, forkhead box G1a antibody, forkhead box G1 antibody, brain factor 1 antibody, forkfead transcription factor G1 antibody, forkhead box G1b antibody, forkhead box G1 L homeolog antibody, foxg1a antibody, foxg1 antibody, bf-1 antibody, Foxg1 antibody, foxg1b antibody, FOXG1 antibody, foxg1.L antibody

Background:

Synonyms: BF 1, BF 2, BF-1, BF-2, BF1, BF2 , Brain factor 1, Brain factor 2, FHKL, FKH2, FKHL1, FKHL2, FKHL2, FKHL3, FKHL4, Forkhead box G1A, Forkhead box G1B, Forkhead box protein G1, Forkhead box protein G1A, Forkhead box protein G1B, Forkhead box protein G1C, Forkhead drosophila homolog like 2, Forkhead like 1, Forkhead like 2, FOXG1_HUMAN.

Background: The winged-helix transcriptional repressor (WH) BF-1 gene encodes brain factor 1 (BF-1), also known as foxg1, and is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon (14). WH proteins are a family of putative transcriptional regulators with diverse roles in development, and are characterized by a highly conserved DNA binding structure, the WH domain (1,5,6). BF-1 plays a critical role in the development of the cerebral hemispheres of the brain and targeted disruption of the gene leads to severe defects in the development of telencephalic structures, such as the cerebral cortex and basal ganglia (1). The loss of BF-1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex (1,7). BF-1 is expressed by E8.5 in telencephalic progenitors (1). It may also regulate the response of cerebral cortical progenitors to environmental cues (1).