HSP70 1A/ 1B (AA 500-600) antibody (HRP)
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- Target
- HSP70 1A/ 1B
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Binding Specificity
- AA 500-600
- Reactivity
- Human, Chicken, Mouse, Pig, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- HRP
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
- Cross-Reactivity
- Chicken, Human, Mouse, Pig, Rat
- Predicted Reactivity
- Cow,Sheep,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human HSP70 1A/1B
- Isotype
- IgG
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- HSP70 1A/ 1B
- Alternative Name
- HSP70 1A/1B
- Background
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Synonyms: HSP72, HSPA1, HSP70I, HSP70-1, HSP70-1A, HEL-S-103, Heat shock 70 kDa protein 1A/1B, Heat shock 70 kDa protein 1/2, HSP70-1/HSP70-2, HSP70.1/HSP70.2, HSPA1A, HSX70
Background: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
- Gene ID
- 3303
- UniProt
- P08107
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