PGGT1B antibody (HRP)
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- Target See all PGGT1B Antibodies
- PGGT1B (Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B))
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PGGT1B antibody is conjugated to HRP
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PGGT1B/FNTB
- Isotype
- IgG
- Top Product
- Discover our top product PGGT1B Primary Antibody
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PGGT1B (Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B))
- Alternative Name
- PGGT1B (PGGT1B Products)
- Synonyms
- MGC115505 antibody, BGGI antibody, GGTI antibody, 2010207C17Rik antibody, 2610100E13 antibody, AI451237 antibody, AI551093 antibody, BGG1 antibody, GGT1 antibody, protein geranylgeranyltransferase type I subunit beta antibody, protein geranylgeranyltransferase type I, beta subunit S homeolog antibody, protein geranylgeranyltransferase type 1 subunit beta antibody, protein geranylgeranyltransferase type I, beta subunit antibody, PGGT1B antibody, pggt1b.S antibody, Pggt1b antibody
- Background
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Synonyms: CAAX farnesyltransferase subunit beta, EC 2.5.1.58, EC=2.5.1.58, Farnesyltransferase, farnesyltransferase CAAX box beta1, farnesyltransferase, CAAX box, beta, FNTB, FNTB_HUMAN, FPTB, FTase beta, FTase-beta, Protein farnesyltransferase subunit beta, RAS proteins prenyltransferase beta, Ras proteins prenyltransferase subunit beta.
Background: Mammalian protein farnesyl transferases are heterodimeric proteins containing two nonidentical Alpha and beta subunits that attach farnesyl residues to a cysteine at the fourth position from the COOH terminus of several proteins, including nuclear lamins and p21Ras proteins. The natural substrates contain the Cys-A-A-Xaa recognition sequence, where the A residues are aliphatic and Xaa represents methionine, serine, glutamine or cysteine. The purified farnesyl transferase is an a-b heterodimer. The beta subunit, which is known as FT beta, CAAX farnesyltransferase subunit beta, or Ras proteins prenyltransferase subunit beta, is a 437 amino acid protein that contains five PFTB repeats and binds the peptide substrate. The Alpha subunit is suspected to participate in formation of a stable complex with the substrate farnesyl pyrophosphate.
- Gene ID
- 2342
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