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PGGT1B antibody (HRP)

PGGT1B Reactivity: Human, Rat, Mouse WB, IHC (p) Host: Rabbit Polyclonal HRP
Catalog No. ABIN1421230
  • Target See all PGGT1B Antibodies
    PGGT1B (Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B))
    Reactivity
    • 19
    • 16
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 16
    • 3
    Rabbit
    Clonality
    • 17
    • 2
    Polyclonal
    Conjugate
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PGGT1B antibody is conjugated to HRP
    Application
    • 18
    • 13
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PGGT1B/FNTB
    Isotype
    IgG
    Top Product
    Discover our top product PGGT1B Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PGGT1B (Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B))
    Alternative Name
    PGGT1B (PGGT1B Products)
    Synonyms
    MGC115505 antibody, BGGI antibody, GGTI antibody, 2010207C17Rik antibody, 2610100E13 antibody, AI451237 antibody, AI551093 antibody, BGG1 antibody, GGT1 antibody, protein geranylgeranyltransferase type I subunit beta antibody, protein geranylgeranyltransferase type I, beta subunit S homeolog antibody, protein geranylgeranyltransferase type 1 subunit beta antibody, protein geranylgeranyltransferase type I, beta subunit antibody, PGGT1B antibody, pggt1b.S antibody, Pggt1b antibody
    Background

    Synonyms: CAAX farnesyltransferase subunit beta, EC 2.5.1.58, EC=2.5.1.58, Farnesyltransferase, farnesyltransferase CAAX box beta1, farnesyltransferase, CAAX box, beta, FNTB, FNTB_HUMAN, FPTB, FTase beta, FTase-beta, Protein farnesyltransferase subunit beta, RAS proteins prenyltransferase beta, Ras proteins prenyltransferase subunit beta.

    Background: Mammalian protein farnesyl transferases are heterodimeric proteins containing two nonidentical Alpha and beta subunits that attach farnesyl residues to a cysteine at the fourth position from the COOH terminus of several proteins, including nuclear lamins and p21Ras proteins. The natural substrates contain the Cys-A-A-Xaa recognition sequence, where the A residues are aliphatic and Xaa represents methionine, serine, glutamine or cysteine. The purified farnesyl transferase is an a-b heterodimer. The beta subunit, which is known as FT beta, CAAX farnesyltransferase subunit beta, or Ras proteins prenyltransferase subunit beta, is a 437 amino acid protein that contains five PFTB repeats and binds the peptide substrate. The Alpha subunit is suspected to participate in formation of a stable complex with the substrate farnesyl pyrophosphate.

    Gene ID
    2342
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