Mannose Receptor antibody (PE-Cy3)

Catalog No. ABIN1430772

Product Details anti-Mannose Receptor Antibody

Target: Mannose Receptor (MR)

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Pig, Sheep, Chicken, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mannose Receptor antibody is conjugated to PE-Cy3

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MRC1

Isotype: IgG

Application Details

Application Notes: WB(1:100-500)
IHC-P(1:100-500)
IF(IHC-P)(1:100-500)

Comment:

Excitation / Emission wavelength: 496 nm / 556 nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Protect from light.

Storage: 4 °C

Storage Comment: Store at -20 °C for 12 months.

Expiry Date: 12 months

Target Details for Mannose Receptor

Target: Mannose Receptor (MR)

Alternative Name: Mannose Receptor (MR Products)

Synonyms: CD206 antibody, CLEC13D antibody, CLEC13DL antibody, MMR antibody, MRC1L1 antibody, bA541I19.1 antibody, AW259686 antibody, MR antibody, mannose receptor C-type 1 antibody, mannose receptor, C type 1 antibody, MRC1 antibody, Mrc1 antibody

Background: The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This gene is in close proximity to MRC1L1. The gene loci including this gene, MRC1L1, as well as LOC340843 and LOC340893, consist of two nearly identical, tandemly linked genomic regions, which are thought to be a part of a duplicated region. [provided by RefSeq].

Molecular Weight: 160 kDa

Gene ID: 4360

HGNC: 0