CYP17A1 antibody (AA 134-144)

Catalog No. ABIN1496019

Product Details anti-CYP17A1 Antibody

Target: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Binding Specificity: AA 134-144

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CYP17A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human CYP17A1.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%) Marmoset, Hamster, Panda, Cat, Horse (91%) Mouse, Sheep, Goat, Elephant, Bat, Bovine, Dog, Rabbit, Opossum, Zebrafish (82%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-LFKDGDQKLEK from an internal region of human CYP17A1 (NP_000093.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%), Marmoset, Hamster, Panda, Cat, Horse (91%), Mouse, Sheep, Goat, Elephant, Bat, Bovine, Dog, Rabbit, Opossum, Zebrafish (82%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:64000), WB (1:64000, 0.1 - 0.3 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CYP17A1

Target: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Alternative Name: CYP17 / CYP17A1 (CYP17A1 Products)

Synonyms: cyp17 antibody, CYPXVII antibody, P450c17 antibody, cyp17a1 antibody, P450-C17 antibody, wu:fi13g04 antibody, wu:fi17b11 antibody, wu:fi31c08 antibody, zgc:136516 antibody, zgc:66494 antibody, P45017A1 antibody, CYP17 antibody, CPT7 antibody, P450C17 antibody, S17AH antibody, Cyp17 antibody, p450c17 antibody, cytochrome P450 17A1 antibody, cytochrome P450, family 17, subfamily A, polypeptide 1 antibody, steroidogenic cytochrome P450 17-hydroxylase/lyase antibody, cytochrome P450 family 17 subfamily A member 1 L homeolog antibody, cytochrome P450 family 17 subfamily A member 1 antibody, cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase antibody, cytochrome P450, family 17, subfamily a, polypeptide 1 antibody, cytochrome P450c17 antibody, CpipJ_CPIJ010537 antibody, CpipJ_CPIJ010543 antibody, PTRG_02047 antibody, cyp17a1 antibody, cyp17 antibody, cyp17a1.L antibody, CYP17A1 antibody, Cyp17a1 antibody

Background: Name/Gene ID: CYP17A1
Family: Cytochrome P450

Synonyms: CYP17A1, CYP17, CYPXVII, CPT7, Cytochrome P450-C17, Cytochrome P450c17, p450C17, Steroid 17-alpha-monooxygenase, Cytochrome P450 17A1, Cytochrome p450 XVIIA1, S17AH

Gene ID: 1586

NCBI Accession: NP_000093

UniProt: P05093

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin